Hwan-Soo Yoo

Yong-Moon Lee4
Jin Tae Hong3
Ki-Wan Oh2
Bang Yeon Hwang2
Kyeong-Mi Choi2
4Yong-Moon Lee
3Jin Tae Hong
2Ki-Wan Oh
2Bang Yeon Hwang
2Kyeong-Mi Choi
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Several studies have been suggested that long-term exposure to stress has detrimental effects on various brain functions and leads to neurodegenerative changes. However, the precise mechanism by which stress induces brain damage or neurodegenerative change is still a matter of debate. This study investigated the damage of neuronal cells involving in the(More)
  • Miran Jo, Hyung-Mun Yun, Kyung-Ran Park, Mi Hee Park, Dong Hun Lee, Seung Hee Cho +10 others
  • 2014
Thiacremonone (2, 4-dihydroxy-2, 5-dimethyl-thiophene-3-one) is an antioxidant substance as a novel sulfur compound generated from High-Temperature-High-Pressure-treated garlic. Peroxiredoxin 6 (PRDX6) is a member of peroxidases, and has glutathione peroxidase and calcium-independent phospholipase A2 (iPLA2) activities. Several studies have demonstrated(More)
Sphingomyelin is the most abundant sphingolipid in mammalian cells and is mostly present in the plasma membrane. A new analytical method using high-performance liquid chromatography (HPLC) was developed to quantify sphingomyelin in mouse plasma and tissues, 3T3-L1 cells, rat aortic smooth muscle cells, and HT-29 cells. Sphingomyelin and(More)
This study was designed to determine whether (-)-epigallocatethin-3-O-gallate (EGCG) could reverse caffeine-induced anxiogenic-like effects in animals. In mice, EGCG antagonized the caffeine-induced reduction in both the open arm entry number and time-spent in open arm on elevated plus-maze. In addition, EGCG also antagonized the caffeine-induced reduction(More)
The discovery of ceramide kinase (CerK), which phosphorylates ceramide (Cer) to ceramide 1-phisphate (C1P), established a new pathway for Cer metabolism. Among mouse tissues, brain contains the highest CerK activity. In this study, we found that CerK is highly expressed in cerebellar Purkinje cells. Since Purkinje cells are important for motor-related(More)
Rapid development of smart devices has lead people to be able to read books through their devices anytime and anywhere. Even though its popularity, e-books have ingrained disadvantages such as: (1) It does not have an expandable scheme that allows readers to add multimedia contents or their emotional expressions to books. (2) It is not easy to add(More)
Obesity, which is characterized by excessive fat accumulation, is associated with several pathological disorders, including metabolic diseases. In this study, the anti-obesity effect of 6,8-diprenylgenistein (DPG), a major isoflavonoid of Cudrania tricuspidata fruits was investigated using high fat-diet (HFD)-induced obese mice at the doses of 10 and 30(More)
  • Chul Ju Hwang, Hyung-Mun Yun, Kyung-Ran Park, Ju Kyung Song, Hyun Ok Seo, Byung Kook Hyun +6 others
  • 2014
Estrogen has been known to reduce the development of Alzheimer’s disease (AD). However, exact mechanisms are not clear. We investigated whether estrogen can increase amyloid-beta (Aβ) degradation and affects Aβ-induced memory impairment in an estrogen deficiency model. Estrogen receptor alpha (ERα) knockout mice and wild-type mice were(More)
(a) (b) (c) (d) Snapshot: (a) crop simulator with sowing seed, (b) crop simulator with disease and insect simulator, (c) economic simulator with buying seeds (d) map tool Abstract We propose an Agritainment (agriculture with entertainment) framework, where users can learn how to cultivate plants and to breed livestock. To make an agricultural training(More)
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