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BACKGROUND The administration of amide-type local anesthetics to cartilaginous tissues has revealed potential chondrotoxicity. PURPOSE This study evaluated whether administration of single doses of 1% lidocaine, 0.25% bupivacaine, and 0.5% ropivacaine resulted in decreased chondrocyte viability or cartilage matrix degradation in vitro. STUDY DESIGN(More)
We present in this paper a simple, yet efficient convolutional neural network (CNN) architecture for robust audio event recognition. Opposing to deep CNN architectures with multiple convolutional and pooling layers topped up with multiple fully connected layers, the proposed network consists of only three layers: convolutional, pooling, and softmax layer.(More)
The human auditory system is very well matched to both human speech and environmental sounds. Therefore, the question arises whether human speech material may provide useful information for training systems for analyzing nonspeech audio signals, such as in a recognition task. To find out how similar nonspeech signals are to speech, we measure the closeness(More)
We introduce in this paper a metric learning approach for automatic sleep stage classification based on single-channel EEG data. We show that learning a global metric from training data instead of using the default Euclidean metric, the k-nearest neighbor classification rule outperforms state-of-the-art methods on Sleep-EDF dataset with various(More)
Despite the success of the automatic speech recognition framework in its own application field, its adaptation to the problem of acoustic event detection has resulted in limited success. In this paper, instead of treating the problem similar to the segmentation and classification tasks in speech recognition, we pose it as a regression task and propose an(More)
The role of the tutor is important in developing effective group process in educational programs built around smallgroup, problem-based learning (PBL). The tutor’s role includes creating a supportive group climate, encouraging the involvement of group members and addressing group problems when they arise. Good tutoring has the potential to enhance group(More)
BACKGROUND This study was designed to determine the effects of pretreatment with an angiotensin receptor blocker on left ventricular (LV) function and remodeling during acute myocardial infarction (MI). METHODS AND RESULTS Sprague-Dawley rats were pretreated with candesartan (10 mg x kg(-1) x d(-1)) for 2 weeks and studied at 1, 3, and 6 minutes after MI.(More)
This paper proposes an approach for the efficient automatic joint detection and localization of single-channel acoustic events using random forest regression. The audio signals are decomposed into multiple densely overlapping superframes annotated with event class labels and their displacements to the temporal starting and ending points of the events. Using(More)
The human auditory system is very well matched to both human speech and environmental sounds. Therefore, the question arises whether human speech material may provide useful information for training systems for analyzing nonspeech audio signals, e.g., in a classification task. In order to answer this question, we consider speech patterns as basic acoustic(More)