In 1973 and 1974, several thousand Michigan dairy farms were contaminated by polybrominated biphenyls (P.B.B.) as the result of an industrial accident. An unknown quantity of contaminated meat and dairy products entered the food chain before contaminated farms were quarantined. To determine the extent of human exposure, P.B.B. concentrations were measured… (More)
BACKGROUND Hepatitis B coinfection is common in HIV-positive individuals and as antiretroviral therapy has made death due to AIDS less common, hepatitis has become increasingly important. Several drugs are available to treat hepatitis B. The most potent and the one with the lowest risk of resistance appears to be tenofovir (TDF). However there are several… (More)
OBJECTIVES For the last 10 years there has been an epidemic of hepatitis C virus (HCV) infection in men who have sex with men (MSM) in Europe, North America and Australia. The majority of those infected are also HIV-positive and it is unclear to what extent HIV-negative MSM are also at increased risk of infection with HCV. This study provides the first… (More)
BACKGROUND Hepatitis B virus (HBV) infection is an increasingly important cause of morbidity and mortality in HIV-infected adults. This study aimed to determine the prevalence and incidence of HBV in the UK CHIC Study, a multicentre observational cohort. METHODS AND FINDINGS 12 HIV treatment centres were included. Of 37,331 patients, 27,450 had at least… (More)
The location, source of infection, and CT characteristics of 90 intracerebral abscesses and 23 subdural empyemas are reported with special regard to capsule enhancement and surrounding cerebral edema.