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In vitro cytotoxic screening of selected Saudi medicinal plants
- Hussein A. Almehdar, H. Abdallah, A. Osman, E. Abdel-Sattar
- BiologyJournal of Natural Medicines
- 1 April 2012
The methanolic extracts of forty species of plants traditionally used in Saudi Arabia for the treatment of a variety of diseases were tested in vitro for their potential anticancer activity on different human cancer cell lines.
Hib Vaccines: Past, Present, and Future Perspectives
Increased knowledge in the fields of immunology, molecular biology, glycobiology, glycoimmunology, and the biology of infectious microorganisms has led to a dramatic increase in vaccine efficacy.
Assessment of genetic diversity in IL‐6 and RANTES promoters and their level in Saudi coronary artery disease patients
The present study consisted of a total of 200 subjects (100 confirmed coronary artery disease (CAD) patients), both men and women, and 100 healthy control individuals.
Divergent Anticancer Activity of Free and Formulated Camel Milk α-Lactalbumin
- V. Uversky, E. El‐Fakharany, Marwa M. Abu‐Serie, Hussein A. Almehdar, E. Redwan
- BiologyCancer investigation
- 26 September 2017
It is shown here that the OA-α-cLA complex does not affect normal cells but has noticeable anti-cancer activity, especially against MCF-7 cells, thus boosting the anticancer activity of α- cLA and improving the selectivity of OA.
Antimicrobial potentials and structural disorder of human and animal defensins.
Acylated pregnane glycosides from Caralluma quadrangula.
Efficient production of lycopene in Saccharomyces cerevisiae by expression of synthetic crt genes from a plasmid harboring the ADH2 promoter.
Assessment of IL‐18 Serum Level and Its Promoter Polymorphisms in the Saudi Coronary Artery Disease (CAD) Patients
Inflammation seems to have a role in the pathogenesis of CAD but not leading to the significant changes at the genetic level, on the basis of the result.
Disorder in Milk Proteins: Lactadherin Multifunctionality and Structure.
- Bassam H Sabha, Fuad Alzahrani, Hussein A. Almehdar, V. Uversky, E. Redwan
- Medicine, ChemistryCurrent protein & peptide science
- 9 August 2018
Lactadherin belongs to the family of secreted extracellular matrix proteins, and clearly can be considered as a multifunctional glycoprotein involved in regulation of many biological and physiological processes, such as angiogenesis, atherosclerosis, haemostasis, phagocytosis, and tissue remodeling.
Biocidal activity of chicken defensin-9 against microbial pathogens.
- H. Yacoub, S. M. El-Hamidy, A. Elazzazy
- BiologyBiochemistry and cell biology = Biochimie et…
- 1 April 2016
Morphological analysis by TEM revealed that sAvBD-9 induces shortening and swelling of Staphylococcus aureus and Shigella sonni cells, opens holes and deep craters in their envelopes, and leads to the release of their cytoplasmic content.