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Associations of a non-synonymous variant in SLC2A9 with gouty arthritis and uric acid levels in Han Chinese subjects and Solomon Islanders
Objective To study the associations of gout, tophi and uric acid levels with the gout-related SLC2A9 (solute carrier family 2, member 9) single nucleotide polymorphisms (SNPs) between two differentExpand
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Genomewide scan for gout in taiwanese aborigines reveals linkage to chromosome 4q25.
Gout is a disorder of uric-acid metabolism. The Pacific Austronesian population, including Taiwanese aborigines, has a remarkably high prevalence of hyperuricemia and gout, which suggests a founderExpand
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The use of tobacco-free betel-quid in conjunction with alcohol/tobacco impacts early-onset age and carcinoma distribution for upper aerodigestive tract cancer.
  • C. Lee, K. Lee, +13 authors Y. Ko
  • Medicine
  • Journal of oral pathology & medicine : official…
  • 1 October 2011
BACKGROUND  Recognition of how risk factors affect the age when cancers are first diagnosed may help to establish more appropriate cancer screening and preventive strategies. METHODS  ToExpand
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Prognostic factors associated with the survival of oral and pharyngeal carcinoma in Taiwan
BackgroundIn Taiwan, a distinct ethnic group variation in incidence and mortality rates has been suggested for most carcinomas. Our aim is to identify the role of prognostic factors associated withExpand
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Monoamine oxidase A gene polymorphisms and enzyme activity associated with risk of gout in Taiwan aborigines
Taiwanese aborigines have a high prevalence of hyperuricemia and gout. Uric acid levels and urate excretion have correlated with dopamine-induced glomerular filtration response. MAOs represent one ofExpand
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Characterization of arecoline-induced effects on cytotoxicity in normal human gingival fibroblasts by global gene expression profiling.
Areca nut is the most widely used psychoactive substance and an important environmental risk factor for development of oral premalignant lesions and cancer. Arecoline, the major alkaloid of arecaExpand
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Distinct SPINK5 and IL‐31 polymorphisms are associated with atopic eczema and non‐atopic hand dermatitis in Taiwanese nursing population
Abstract:  The term ‘hand dermatitis’ describes inflammatory skin condition localized to the hands. Nurses working at hospital settings are prone to develop hand dermatitis. The current study aimedExpand
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The SLC22A12 gene is associated with gout in Han Chinese and Solomon Islanders
Gout is characterised by monosodium urate crystals in hyperuricaemic individuals.1 2 Impaired excretion of urate exacerbates this condition.1 Urate transporter 1 (encoded by SLC22A12 ) is anExpand
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Prevalence and associated factors of betel quid use in the Solomon Islands: a hyperendemic area for oral and pharyngeal cancer.
Chewing betel quid is a popular habit in tropical areas. It is also a known fact that oral cancer is one of the most common cancers in the Solomon Islands, where betel quid chewing is prevalent. ThisExpand
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ALPK1 genetic regulation and risk in relation to gout.
BACKGROUND The present study investigated whether single nucleotide polymorphisms (SNPs) in the alpha-protein kinase 1 (ALPK1) gene are associated with gout in aboriginal and Han Chinese Taiwanese.Expand
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