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Sarcopenia is a geriatric syndrome in which there is a decrease of muscle mass and strength with aging. In age-related loss of muscle strength, there are numerous observations supporting the assertion that neural factors mediate muscle strength. A possible contributing cause may be that aging changes systemic extracellular heat shock protein (eHsp)72(More)
This study longitudinally examined the relationships between the specific domains of cognitive performance and functional decline among the community elderly. The study population was 119 men and 194 women aged 70-84 at baseline, who were examined at both baseline and in a 4-year follow-up survey. Katz's Index and the Tokyo Metropolitan Institute of(More)
BACKGROUND Cognitive function is an important contributor to health among elderly adults. One reliable measure of cognitive functioning is information processing speed, which can predict incident dementia and is longitudinally related to the incidence of functional dependence. Few studies have examined the association between information processing speed(More)
OBJECTIVE This study aimed to clarify the longitudinal relationship between leisure activities and cognitive decline among Japanese community-dwelling older adults, using a 5-year prospective cohort study design. METHODS A total of 567 men and women, aged 70years and over, participated in the study. The Mini-Mental State Examination was used in baseline(More)
OBJECTIVE To investigate the combined and separate effects of exercise and milk fat globule membrane (MFGM) supplementation on frailty, physical function, physical activity level, and hematological parameters in community-dwelling elderly Japanese women. METHODS A total of 131 frail, elderly women over 75 years were randomly assigned to one of four(More)
OBJECTIVE The aim of this study is to examine the relationship between personality traits and participation in mass health checkups among Japanese community-dwelling elderly. METHODS A data set of 327 men and 519 women aged 70 years and over was used in the analysis. The NEO Five-Factor Inventory was administered to assess the "big five" personality(More)
OBJECTIVE We sought to examine the longitudinal relationship between cognitive function and all-cause mortality among Japanese community-dwelling older adults, using an 8-year prospective cohort study design with mortality surveillance. METHODS A total of 454 men and 386 women, aged 70 years and older, participated in the study. The Mini Mental State(More)
AIMS Urinary incontinence (UI) and musculoskeletal conditions, particularly low back pain (LBP), and osteoarthritis (OA), are common problems that have been associated with mobility limitations and future dependence in activities of daily living in the elderly. The purpose of this study was to explore the relationship between UI, UI types, and(More)
PURPOSE This study was conducted to examine age-related differences in cognitive function, and their relation to higher-level competence of elderly living in an urban community. METHOD Participants were 438 individuals (males 168, females 270) aged 70 to 84 years living in an urban community in Tokyo. Three cognitive performance tests, the Wechsler Adult(More)
BACKGROUND Somatic afferent nerve stimuli are used for treating an overactive bladder (OAB), a major cause of nocturia in the elderly. Clinical evidence for this treatment is insufficient because of the lack of appropriate control stimuli. Recent studies on anesthetized animals show that gentle stimuli applied to perineal skin with a roller could inhibit(More)