Humberto Villavicencio

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PURPOSE To develop an accurate and noninvasive method for bladder cancer diagnosis and prediction of disease aggressiveness based on the gene expression patterns of urine samples. EXPERIMENTAL DESIGN Gene expression patterns of 341 urine samples from bladder urothelial cell carcinoma (UCC) patients and 235 controls were analyzed via TaqMan Arrays. In a(More)
We evaluated the performance of a multiprobe FISH (fluorescence in situ hybridization) assay for noninvasive detection of superficial urothelial carcinoma (UC) in the bladder, in comparison to urinary cytology. Voided urine samples from 74 patients with superficial UC were analyzed by both techniques. Urine samples from 19 patients with muscle-invasive(More)
OBJECTIVES To assess the clinical utility of a fluorescence in situ hybridization (FISH) assay as a non-invasive method for diagnosing and monitoring urothelial carcinoma (UC) in the upper urinary tract (UUT). METHODS Urine specimens from 30 consecutive patients with UUT UC and 19 healthy controls were analyzed by means of cytology and FISH. For FISH(More)
AIMS To evaluate the outcomes, complications, and quality of life of patients after a Remeex re-adjustable sling for recurrent stress urinary incontinence (SUI) and intrinsic sphincteric deficiency (ISD) indications. METHODS One hundred twenty-five patients with SUI were prospectively evaluated following a re-adjustable sling in a single tertiary academic(More)
OBJECTIVE To evaluate the use of a multiprobe fluorescent in situ hybridization (FISH) assay for determining the response of patients with high-risk superficial bladder tumour (HRSBT) to bacillus Calmette-Guérin (BCG) therapy. METHODS Bladder washing specimens from 65 HRSBT patients collected before and after BCG therapy were analyzed by FISH. Labelled(More)
OBJECTIVES To evaluate the risk factors for disease progression in the frequent subgroup of Stage T1G2 (World Health Organization 1973) bladder tumors using an analysis of a large cohort of patients with Stage T1G2 disease. METHODS A cohort of 616 patients with Stage T1G2 were treated with transurethral resection and random bladder biopsies. The mean(More)
Urothelial bladder cancer represents a heterogeneous disease with divergent pathways of tumorigenesis. Tumor invasion and progression are a multifactorial process promoted by microenvironmental changes that include overexpression of matrix metalloproteinases (MMPs). Recent data clearly challenge the classic dogma that MMPs promote metastasis only by(More)
OBJECTIVE To report a rare case of a Spontaneous perirenal haematoma due to Polyarteritis nodosa treated with a selective embolización of the bleeding aneurysm. Polyarteritis nodosa (PAN) is one of a spectrum of diseases thet belongs to the pathologic category of necrotizing vasculitis. Spontaneous perirenal haematoma (SPH) is an unusual complication of(More)
PURPOSE Describe morbidity and survival in patients older than 80 years with muscle invasive bladder cancer (MIBC) treated with radical cystectomy (RC) or transurethral resection (TUR) in our institution. MATERIALS AND METHODS We reviewed our database of all patients older than 80 years treated with RC and TUR for MIBC between 1993 and 2005 in our(More)
  • References Pichler, P Ranjan, +17 authors Lerma Puertas
  • 2017
Figure 2 Total rupture of the urethra at the prostatomem-branous junction (combined retrograde and anterograde urethrogram with suprapubic cystostomy). Case 3. Male aged 12 years with pelvic trauma (crushing) and rupture of the prostatic urethra (Fig. 2). Primary endoscopic realignment was performed. Endoscopic internal urethrotomies were performed at 5, 6,(More)