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We report a case of adenocarcinoma of the tail of the pancreas which was manifested by metastases to the spermatic cord and epididymis. 8.1% of the malignant tumors of the spermatic cord and/or epididymis are metastatic. After reviewing the literature on this subject, we found that the most frequent primary tumors metastatic to the spermatic cord and(More)
BACKGROUND The prognostic significance of venous involvement and tumour thrombus level in renal cell carcinoma (RCC) remains highly controversial. In 2010, the American Joint Committee on Cancer (AJCC) and the Union International Centre le Cancer (UICC) revised the RCC staging system (7th edition) based on tumour thrombus level, differentiating the T stage(More)
OBJECTIVES To review our experience in 14 patients who underwent supravesical urinary diversion maintaining their defunctionalized bladder in situ. METHODS A variety of pathological entities indicated surgery, including neurogenic bladder, urinary tuberculosis (with severely contracted bladder), interstitial cystitis, and retroperitoneal fibrosis. (More)
BACKGROUND Bacillus Calmette-Guérin (BCG) is a standard treatment for reducing tumour recurrence and delaying progression of high-risk non-muscle-invasive bladder tumours. However, it is not clear yet which patients are more likely to respond to BCG. OBJECTIVE To evaluate the role of the methylation of 25 tumour suppressor genes (TSG) as clinical outcome(More)
We evaluated the performance of a multiprobe FISH (fluorescence in situ hybridization) assay for noninvasive detection of superficial urothelial carcinoma (UC) in the bladder, in comparison to urinary cytology. Voided urine samples from 74 patients with superficial UC were analyzed by both techniques. Urine samples from 19 patients with muscle-invasive(More)
BACKGROUND Bacillus Calmette-Guérin (BCG) is a standard treatment for reducing tumour recurrence and delaying progression of high-risk, non-muscle-invasive bladder tumours. However, it is not clear yet which patients are more likely to be responders to BCG. OBJECTIVE To evaluate the role of ezrin expression in bladder cancer (BCa) progression in T1G3(More)
PURPOSE There is a need in urological practice to identify new bladder cancer molecular markers to further develop noninvasive diagnostic tests. We analyzed bladder cancer gene expression profiles to determine the relevant differentially expressed genes and whether this differential expression is maintained in urine samples. MATERIALS AND METHODS We(More)
Primary renal aspergillosis is a very rare complication of AIDS which usually have fatal outcome (53% of mortality). The immune status of the patient and the early and correct therapeutic approach are the main factors that predict disease advancement. The new antiretroviral therapies improve the CD4 cell count and permit to treat these patients as(More)
OBJECTIVE To investigate the morphological diagnostic criteria and biology of the urinary bladder small cell carcinoma (SCC). METHODS Study of 23 cases of bladder SCC, looking for the clinical presentation, pathological features and evolution, and review of 134 previously published cases. RESULTS The SCC is infrequent (0.48-1%), 50% of them have areas(More)
BACKGROUND Controversy exists over the most important prognostic factors in T1 high-grade non-muscle-invasive bladder cancer (NMIBC) patients treated with bacillus Calmette-Guérin (BCG). OBJECTIVE Evaluate prognostic factors for recurrence, progression, and disease-specific mortality after adjuvant intravesical BCG immunotherapy in patients with T1G3(More)