Huizhong Shou

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The hypothesized variable expression of polymorphic membrane proteins (PmpA-PmpI) in Chlamydia trachomatis-infected patients was tested by examination of the expression of each Pmp subtype in in vitro-grown C. trachomatis. A panel of monospecific polyclonal and monoclonal antibodies was used to demonstrate surface exposure of Pmps of each subtype by(More)
We developed an RNA-Seq-based method to simultaneously capture prokaryotic and eukaryotic expression profiles of cells infected with intracellular bacteria. As proof of principle, this method was applied to Chlamydia trachomatis-infected epithelial cell monolayers in vitro, successfully obtaining transcriptomes of both C. trachomatis and the host cells at 1(More)
Genomic analysis of the Chlamydiaceae has revealed a multigene family encoding large, putatively autotransported polymorphic membrane proteins (Pmps) with nine members in the sexually transmitted pathogen Chlamydia trachomatis. While various pathogenesis-related functions are emerging for the Pmps, observed genotypic and phenotypic variation among several(More)
Effect of Chlamydiaphage CPG1 on the Course of Conjunctival Infection with “Chlamydia caviae” in Guinea Pigs Roger G. Rank,* Anne K. Bowlin, Stefania Cané, Huizhong Shou, Zhi Liu, Uma M. Nagarajan, and Patrik M. Bavoil Departments of Microbiology and Immunology and Pediatrics, University of Arkansas for Medical Sciences and Arkansas Children’s Hospital(More)
Over the last several years, four different phages of chlamydiae, in addition to a phage associated with Chlamydia psittaci isolated from an ornithosis infection in ducks over 25 years ago, have been described and characterized. While these phages and their chlamydial host specificities have been characterized in vitro, there is virtually nothing known(More)
OBJECTIVE To determine the epidemiologic patterns of subgroups A and B and genotypes of respiratory syncytial viruses (RSV) during two uncontinuously epidemic years from 1990 to 1991 and 1997 to 1998 in Beijing. METHODS Nasopharyngeal secretion (NPS) samples of RSV positive or BSV isolates tested by indirect immunofluorescent (IIF) assay were classified(More)
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