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After interleukin-12p40, are interleukin-23 and interleukin-17 the next therapeutic targets for inflammatory bowel disease?
Inflammatory bowel disease (IBD), typified by Crohn's disease and ulcerative colitis, is a common disorder characterized by recurrent and serious inflammation of the gastrointestinal tract. RecentExpand
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The NOD2 defect in Blau syndrome does not result in excess interleukin-1 activity.
OBJECTIVE Blau syndrome is a rare, autosomal-dominant, autoinflammatory disorder characterized by granulomatous arthritis, uveitis, and dermatitis. Genetics studies have shown that the disease isExpand
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Pediatric eosinophilic esophagitis: Single‐center experience in northwestern USA
Background:  Eosinophilic esophagitis (EE) is an emerging disease. Its incidence and prevalence have been exponentially increasing in the last decade. The clinical manifestations of EE varyExpand
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Vitamin D-deficiency induces eosinophil spontaneous activation.
Eosinophils (Eo) play a critical role in immunity and immune inflammation. The maintenance of Eo homeostasis is not fully understood yet. Vitamin D (VitD) is involved in the regulation of a largeExpand
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Clinicopathological and Ileocolonoscopic Characteristics in Patients with Nodular Lymphoid Hyperplasia in the Terminal Ileum
Nodular lymphoid hyperplasia (NLH) in the small intestine is a rare benign lesion, characterized by the presence of multiple small nodules on the surface of the intestine. To define theExpand
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Carbohydrate and plant hormone regulate the alkali stress response of hexaploid wheat (Triticum aestivum L.)
Abstract Most types of stress influence crop plants at intervals. Unlike other stresses, salt and alkali stresses influence crop plants for their entire life cycle. However, little is known aboutExpand
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First Case Report of Psychological Support and Hospice Care for Terminally Ill Chinese University Student
This case study reports the first successful case of hospice care provided to a Chinese university student in her terminal stage of life. The hospice care and psychological support enabled theExpand
Effect of Danshen injection on expression of TNF-α, IL-6 and MMP-3 in articular cartilage of rabbits with knee osteoarthritis
Objective To study the expression of tumor necrosis factor-α(TNF-α), interleukin(IL)-6, matrix metalloproteinase-3 (MMP-3) in the articular cartilage of rabbits with knee osteoarthritis (KOA)Expand