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Protein poly ADP-ribosylation (PARylation) is a widespread post-translational modification at DNA lesions, which is catalyzed by poly(ADP-ribose) polymerases (PARPs). This modification regulates a number of biological processes including chromatin reorganization, DNA damage response (DDR), transcriptional regulation, apoptosis, and mitosis. PARP1,(More)
Urinary tract infections (UTIs) are one of the most common bacterial infections in humans, causing cystitis, pyelonephritis, and renal failure. Uropathogenic Escherichia coli (UPEC) is the leading cause of UTIs. Accurate and rapid discrimination of UPEC lineages is useful for epidemiological surveillance. Fimbriae are necessary for the adherence of UPEC(More)
This paper presents the design of a driver amplifier for 1.6 GHz navigation transmitter application based on 0.35um RF CMOS process. In this work, a two-stage topology is proposed. The first stage employs two parallel transistors working in class AB and B mode respectively to improve the linearity and efficiency of the driver. The second stage utilizes a(More)
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