Huirong Han

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Although the innate immune response to induce postischemic inflammation is considered as an essential step in the progression of cerebral ischemia injury, the role of innate immunity mediator NLRP3 in the pathogenesis of ischemic stroke is unknown. In this study, focal ischemia was induced by middle cerebral artery occlusion in NLRP3(-/-), NOX2(-/-), or(More)
The present study was performed to investigate the role of calcitonin gene-related peptide (CGRP) and its receptor in nociception in the basolateral nucleus of amygdala (BLA) of rats. Hindpaw withdrawal latencies (HWLs) to noxious thermal and mechanical stimulations were measured by hot plate and Randall Selitto tests. The HWL to both thermal and mechanical(More)
Is a 2-dimensional (2D) force feedback device capable of presenting 3-dimensional (3D) shapes? The answer is a qualified "yes." "Force shading", a haptic counterpart of bump mapping in computer graphics, presents a non-flat shape on a nominally flat surface by varying the force vector direction in haptic rendering [Morgenbesser and Srinivasan(More)
Lysophosphatidic acid (LPA) is a bioactive phospholipid that activates at least five known G-protein-coupled receptors (GPCRs): LPA1-LPA5. The nervous system is a major locus for LPA1 expression. LPA has been shown to regulate neuronal proliferation, migration, and differentiation during central nervous system development as well as neuronal survival.(More)
The aim of this study was to examine the association between the-149C>T polymorphism of DNA methyltransferase 3B (DNMT3B) and colorectal cancer (CRC) susceptibility. A comprehensive search was conducted to identify all case-control studies of the-149C>T polymor-phism of DNMT3B and CRC risk. Statistical analysis was performed with the software program Stata(More)
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