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Characterization of p38 MAPK isoforms for drug resistance study using systems biology approach
tl;dr
MOTIVATION p38 mitogen-activated protein kinase activation plays an important role in resistance to chemotherapeutic cytotoxic drugs in treating multiple myeloma (MM). Expand
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Robotic-assisted compared with conventional total hip arthroplasty: systematic review and meta-analysis
Background Robotic-assisted total hip arthroplasty (THA) allows for accurate preoperative planning and component positioning, potentially enhancing implant survival and long-term outcomes. TheExpand
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Interclonal gradient of virulence in the Pseudomonas aeruginosa pangenome from disease and environment.
The population genomics of Pseudomonas aeruginosa was analysed by genome sequencing of representative strains of the 15 most frequent clonal complexes in the P. aeruginosa population and of the fiveExpand
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Prediction of treatment efficacy for prostate cancer using a mathematical model
Prostate immune system plays a critical role in the regulation of prostate cancer development regarding androgen-deprivation therapy (ADT) and/or immunotherapy (vaccination). In this study, weExpand
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Integrating multi-scale blob/curvilinear detector techniques and multi-level sets for automated segmentation of stem cell images
tl;dr
We propose a new, automated scheme for stem cell segmentation that combines multi-scale blob and curvilinear structure detectors to delineate the skeletons of stem cells. Expand
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  • Open Access
Systemic modeling myeloma-osteoclast interactions under normoxic/hypoxic condition using a novel computational approach
Interaction of myeloma cells with osteoclasts (OC) can enhance tumor cell expansion through activation of complex signaling transduction networks. Both cells reside in the bone marrow, a hypoxicExpand
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Prognostic value of intraoperative MEP signal improvement during surgical treatment of cervical compressive myelopathy
PurposeThe purpose of the current study was to evaluate the prognostic value of intraoperative improved transcranial motor evoked potential (MEP) after cervical cord decompressive surgery forExpand
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Predicting the impact of combined therapies on myeloma cell growth using a hybrid multi-scale agent-based model
Multiple myeloma is a malignant still incurable plasma cell disorder. This is due to refractory disease relapse, immune impairment, and development of multi-drug resistance. The growth of malignantExpand
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  • Open Access
The effectiveness and safety of preoperative use of erythropoietin in patients scheduled for total hip or knee arthroplasty
Introduction:Because allogeneic blood transfusion carries a risk of serious complications, erythropoietin (EPO) has been used in patients scheduled for total hip or knee arthroplasty in an effort toExpand
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An Efficient and Fast Algorithm for Estimating the Frequencies of 2-D Superimposed Exponential Signals in Presence of Multiplicative and Additive Noise
tl;dr
In this paper, we consider the two-dimensional (2-D) superimposed exponential signals in independently and identically distributed (i.i.d.) multiplicative and additive noise. Expand
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