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Successful expansion of hematopoietic stem cells (HSCs) would benefit the use of HSC transplants in the clinic. Angiopoietin-like 7 promotes the expansion of hematopoietic stem and progenitor cells (HSPC) in vitro and ex vivo. However, the impact of loss of Angptl7 on HSPCs in vivo has not been characterized. Here, we generated Angptl7-deficient mice by(More)
BACKGROUND The mouse is an organism that is widely used as a mammalian model for studying human physiology or disease, and the development of immunodeficient mice has provided a valuable tool for basic and applied human disease research. Following the development of large-scale mouse knockout programs and genome-editing tools, it has become increasingly(More)
with the rapid development of international strategy of nuclear power enterprises in China, the IT department in nuclear power enterprises has been facing the new challenges with high-speed development of businesses. In order to satisfy the development requirements and provide powerful IT service during the production and operation, IT department had(More)
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