Min Zhuo27
Long-Jun Wu25
27Min Zhuo
25Long-Jun Wu
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  • Hansen Wang, Long-Jun Wu, Susan S. Kim, Frank J.S. Lee, Bo Gong, Hiroki Toyoda +6 others
  • 2008
The fragile X mental retardation protein (FMRP) is an RNA-binding protein that controls translational efficiency and regulates synaptic plasticity. Here, we report that FMRP is involved in dopamine (DA) modulation of synaptic potentiation. AMPA glutamate receptor subtype 1 (GluR1) surface expression and phosphorylation in response to D1 receptor stimulation(More)
  • Ming-Gao Zhao, Hiroki Toyoda, Yong-Seok Lee, Long-Jun Wu, Shanelle W. Ko, Xue-Han Zhang +6 others
  • 2005
Cortical plasticity is thought to be important for the establishment, consolidation, and retrieval of permanent memory. Hippocampal long-term potentiation (LTP), a cellular mechanism of learning and memory, requires the activation of glutamate N-methyl-D-aspartate (NMDA) receptors. In particular, it has been suggested that NR2A-containing NMDA receptors are(More)
Previous studies have suggested that calcium/calmodulin-dependent protein kinase IV (CaMKIV) functions as a positive regulator for memory formation and that age-related memory deficits are the result of dysfunctional signaling pathways mediated by cAMP response element-binding protein (CREB), the downstream transcription factor of CaMKIV. Little is known,(More)
The L-type Ca(2+) channel Ca(v)1.2 forms macromolecular signaling complexes that comprise the β(2) adrenergic receptor, trimeric G(s) protein, adenylyl cyclase, and cAMP-dependent protein kinase (PKA) for efficient signaling in heart and brain. The protein phosphatases PP2A and PP2B are part of this complex. PP2A counteracts increase in Ca(v)1.2 channel(More)
We present a semi-automatic and efficient method for producing full polygonal models of range scanned trees, which are initially represented as sparse point clouds. First, a skeleton of the trunk and main branches of the tree is produced based on the scanned point clouds. Due to the unavoidable incompleteness of the point clouds produced by range scans of(More)
In ad hoc sensor networks, sensor nodes have very limited energy resources , thus energy consuming operations such as data collection, transmission and reception must be kept at a minimum. This paper applies particle swarm optimization (PSO) approach to optimize the coverage in ad hoc sensor networks deployment and to reduce cost by clustering method based(More)
Unraveling the mechanisms by which the molecular manipulation of genes of interest enhances cognitive function is important to establish genetic therapies for cognitive disorders. Although CREB is thought to positively regulate formation of long-term memory (LTM), gain-of-function effects of CREB remain poorly understood, especially at the behavioral level.(More)
Pathogens and cellular danger signals activate sensors such as RIG-I and NLRP3 to produce robust immune and inflammatory responses through respective adaptor proteins MAVS and ASC, which harbor essential N-terminal CARD and PYRIN domains, respectively. Here, we show that CARD and PYRIN function as bona fide prions in yeast and that their prion forms are(More)