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The rolling circle amplification (RCA) is a versatile DNA amplification method in which a DNA molecule is amplified using a single DNA primer, allowing the product to be counted as a single dot. Circular templates for RCA can arise from padlock probes in highly specific DNA target-mediated ligation reactions. However, improvement of detection efficiency(More)
A novel pedestrian behavior model is proposed, which integrates 1) Extended Decision Field Theory (EDFT) for tactical level human decision-making, 2) Social Force model (SFM) to represent physical interactions and congestions among the people and the environment, and 3) dynamic planning algorithm involving AND/OR graphs. Furthermore, the Social Force model(More)
In industry, many problems are considered as the Decentralized Resource-Constrained Multi-Project Scheduling Problem (DRCMPSP). Existing approaches encounter difficulties in dealing with large problems while preserving information privacy of project agents. In this paper, we propose a novel approach to solve DRCMPSP based on the multi-unit combinatorial(More)
Globally distributed software enhancement necessitates joint efforts of workforces across various organizations, which constitutes a multifaceted social network. Here, we propose a novel modeling framework to optimally assign the workforce to software development projects considering both short and long-term benefits of the organization. The proposed(More)
This work proposes an agent-based simulation system to address challenges in resource constrained multi project scheduling for a technology intensive industrial product development programme. The system aims at helping users develop robust programme schedules by taking care of intraand interdependencies between projects, potential knock-on effect of(More)
Modeling human decision-making behaviors under a complex and uncertain environment is quite challenging. The goal of this tutorial is to discuss an extended Belief-Desire-Intention (BDI) framework that the authors' research group has been developing last decade to meet such a challenge, integrating models and techniques (e.g. Bayesian Belief Network,(More)
  • Hui Xi
  • Winter Simulation Conference
  • 2012
A multi-scale simulation framework is proposed to analyze pedestrian delays at signalized crosswalks in large urban areas under different conditions. An aggregated-level model runs in normal conditions, where each crosswalk is represented as an agent. A derived probability function extended from Adams' model is utilized to estimate an average pedestrian(More)
In industry, many problems are considered as the decentralized resource-constrained multi-project scheduling problem (DRCMPSP). Existing approaches encounter difficulties in dealing with large DRCMPSP cases while respecting the information privacy requirements of the project agents. In this paper, we tackle DRCMPSP by formulating it as a multi-unit(More)