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Glycosylation is a ubiquitous reaction controlling the bioactivity and storage of plant natural products. Glycosylation of small molecules is catalyzed by a superfamily of glycosyltransferases (GTs) in most plant species studied to date. We present crystal structures of the UDP flavonoid/triterpene GT UGT71G1 from Medicago truncatula bound to UDP or(More)
Luo et al. proposed a new method to design the maximally permissive and efficient supervisor for enforcing linear constraints on an ordinary Petri net with uncontrollable transitions. In order to develop this method, Theorem 3 is given. It is clamed that " a linear constraint can be equivalently transformed at an uncontrollable transition into a disjunction(More)
Abnormal accumulation of soluble amyloid beta (Aβ) is believed to cause malfunction of neurons in Alzheimer's disease (AD). The hippocampus is one of the earliest affected brain regions in AD. However, little effort has been made to investigate the effects of soluble Aβ1-42 oligomers on discharge properties of hippocampal neurons in vivo. This study was(More)
There is little known about the regulation of gene expression during TCR-mediated differentiation of immature CD4+8+ (double positive) thymocytes into mature T cells. Using the DPK CD4+8+ thymocyte precursor cell line, we demonstrate that the early growth response-1 gene (Erg-1), encoding a zinc finger transcription factor, is rapidly upregulated after TCR(More)
A power management and computation methodology is proposed for ultra-low power energy harvesting applications. An integrated exponential charge pump that accepts an input voltage of around 150mV and provides an unregulated output voltage of more than 1.5V serves as the power supply. To cater with the fluctuated energy source and unregulated power supply, a(More)
A micro power management system is presented for solar energy harvesting applications. An inductor-less solution is proposed which facilitates on-chip integration of the system. We target at applications working in different lighting environments ranging from strong sunlight to dim indoor lighting where the output voltage from the photovoltaic (PV) cells is(More)