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Articulated hand pose estimation plays an important role in human-computer interaction. Despite the recent progress, the accuracy of existing methods is still not satisfactory, partially due to the difficulty of embedded high-dimensional and non-linear regression problem. Different from the existing discriminative methods that regress for the hand pose with(More)
Neuroinflammation plays an important role in cerebral ischemia/reperfusion (I/R) injury. The P2X7 receptor (P2X7R) has been reported to be involved in the inflammatory response of many central nervous system diseases. However, the role of P2X7Rs in transient global cerebral I/R injury remains unclear. The purpose of this study is to determine the effects of(More)
PURPOSE NOTCH signaling pathway is essential in T-cell development and NOTCH1 mutations are frequently present in T-cell acute lymphoblastic leukemia (T-ALL). To gain insight into its clinical significance, NOTCH1 mutation was investigated in 77 patients with T-ALL. EXPERIMENTAL DESIGN Detection of NOTCH1 mutation was done using reverse transcription-PCR(More)
The spread of the bla(NDM-1) gene is gaining worldwide attentions. This gene is usually carried by large plasmids and has been discovered in diverse bacteria since it was originally found in Klebsiella pneumoniae. Here we report the complete sequences of a bla(NDM-1)-bearing plasmid, pNDM-BJ01, and its variant, pNDM-BJ02, isolated from clinical(More)
We present a vision-based approach for robust 3D fingertip and palm tracking on depth images using a single Kinect sensor. First the hand is segmented in the depth images by applying depth and morphological constraints. The palm is located by performing distance transform to the hand contour and tracked with a Kalman filter. The fingertips are detected by(More)
In the EMIME project we have studied unsupervised cross-lingual speaker adaptation. We have employed an HMM statistical framework for both speech recognition and synthesis which provides transformation mechanisms to adapt the synthesized voice in TTS (text-to-speech) using the recognized voice in ASR (automatic speech recognition). An important application(More)
There has been increasing interest in the use of unsupervised adaptation for the personalisation of text-to-speech (TTS) voices, particularly in the context of speech-to-speech translation. This requires that we are able to generate adaptation transforms from the output of an automatic speech recognition (ASR) system. An approach that utilises unified ASR(More)
Recently, the rs3129882 variant in intron 1 of HLA-DRA was found to be associated with late-onset sporadic Parkinson disease (PD) in Americans of European ancestry. To evaluate whether the same variant is related to PD in Chinese population, we investigated late-onset sporadic PD patients of Chinese Han ethanicity in Mainland China. We found significant(More)
Thiamine (vitamin B(1)) is an essential compound for organisms. It contains a pyrimidine ring structure and a thiazole ring structure. These two moieties of thiamine are synthesized independently and then coupled together. Here we report the molecular characterization of AtTHIC, which is involved in thiamine biosynthesis in Arabidopsis. AtTHIC is similar to(More)