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Interleukin gene polymorphisms in age-related macular degeneration.
TLDR
The data suggest that Taiwan Chinese carriers of the IL-8 +781 T allele, independent of the CFH Y402H polymorphism, are at increased risk of developing wet AMD.
The TGFbeta1 gene codon 10 polymorphism contributes to the genetic predisposition to high myopia.
TLDR
Varied expression of this gene may contribute to the genetic predisposition to high myopia in Chinese Taiwanese, indicating people with the CC homozygote may be at a higher risk of developing highMyopia.
Flavones inhibit breast cancer proliferation through the Akt/FOXO3a signaling pathway
TLDR
Flavone, apigenin and luteolin showed potent inhibitory effects on the proliferation of Hs578T, MDA-MB-231 and MCF-7 breast cancer cells in a concentration and time-dependent manner, which suggest that flavone, Apigen in and lutenolin will be the potential leads for the preventing and treating of breast cancer.
TUMOR NECROSIS FACTOR-α GENE POLYMORPHISMS IN AGE-RELATED MACULAR DEGENERATION
TLDR
The data indicate that the tumor necrosis factor-α −1031 T/C polymorphism may be associated with wet AMD in the Taiwan Chinese population.
Association of interleukin 1beta and receptor antagonist gene polymorphisms with primary open-angle glaucoma.
TLDR
The frequency of the E2 allele of the IL-1beta exon 5 polymorphism was high inPOAG patients and can be used as a marker to predict or search for the genetic causes of glaucoma in Chinese POAG patients.
A novel genetic variant of BMP2K contributes to high myopia
TLDR
Data suggest that BMP2K gene 1379 G/A variant is strongly correlated with high myopia and may contribute to a genetic risk factor for high degrees of myopic pathogenesis.
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