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Cytotoxicity and modes of action of three naturally occurring xanthones (8-hydroxycudraxanthone G, morusignin I and cudraxanthone I) against sensitive and multidrug-resistant cancer cell lines.
TLDR
The cytotoxicity of the studied xanthones and especially compound 3 deserve more detailed exploration in the future to develop novel anticancer drugs against sensitive and otherwise drug-resistant phenotypes. Expand
Cytotoxicity of a naturally occurring furoquinoline alkaloid and four acridone alkaloids towards multi-factorial drug-resistant cancer cells.
TLDR
The five tested alkaloids and mostly acridone 5 are potential cytotoxic natural products that deserve more investigations to develop novel cytotoxicity compounds against multifactorial drug-resistant cancers. Expand
Antibacterial constituents of three Cameroonian medicinal plants: Garcinia nobilis, Oricia suaveolens and Balsamocitrus camerunensis
TLDR
The results of the present investigation provide evidence that the crude extract from G. nobilis, O. suaveolens and B. camerunensis as well as some of their compounds, and mostly compound 2 (isolated from the most active extract GNB), could be considered as interesting natural antibacterial products. Expand
Xanthones inhibitors of α-glucosidase and glycation from Garcinia nobilis
Abstract One new xanthone, caroxanthone ( 1 ) together with six known xanthones, 4-prenyl-2-(3,7-dimethyl-2,6-octadienyl)-1,3,5,8-tetrahydroxyxanthone ( 2 ), smeathxanthone A ( 3 ), gartanin ( 4 ),Expand
Anti-inflammatory activity of benzophenone and xanthone derivatives isolated from Garcinia (Clusiaceae) species
Abstract Species of the genus Garcinia have been the source of many benzophenone and xanthone derivatives. Recent data regarding potent biological properties of natural compounds in Garcinia speciesExpand
A new xanthone derivative from twigs of Garcinia nobilis
TLDR
Phytochemical investigation of the twigs of Garcinia nobilis led to the isolation of a new xanthone, named l-hydroxy-2,5-dimethoxyxanthone (1), together with 15 known compounds, which were tested for their cytotoxic activity against human cervix carcinoma cell line KB-3-1. Expand
Antibacterial and antioxidant xanthones and benzophenone from garcinia smeathmannii.
TLDR
Compounds 1, 2, and 3 exhibited the most prominent antibacterial activity against gram-positive Enterococcus faecalis with minimal inhibitory concentration values of 8, 8, and 2 µg/mL, respectively, while compounds 1, 3, 4, and 6 showed the capacity to scavenge free radicals. Expand
Cytotoxic Compounds from the Leaves of Garcinia polyantha.
The new compound banganxanthone C (I) is isolated from the leaves of Garcinia polyantha together with five known compounds.
Cytotoxic Compounds from the Leaves of Garcinia polyantha
TLDR
A new compound, named banganxanthone C, exhibited significant antiproliferative activity against the leukemia cell line TPH‐1 with IC50 inhibition values of 1.5 and 2.8 μg/ml, respectively and was found to be related to apoptosis induction. Expand
Antiproliferative activity of a new xanthone derivative from leaves of Garcinia nobilis Engl.
TLDR
A new xanthone was isolated from the leaves of Garcinia nobilis Engl. Expand