Hugo Schönenberger Oliveira

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BACKGROUND Psoriasis vulgaris is a chronic recurrent inflammatory skin disease and psoriatic lesions have shown leucocyte infiltration. OBJECTIVES We aimed to study C-reactive protein (CRP) and leucocyte activation markers/inhibitors as potential monitors of psoriasis vulgaris. METHODS A cross-sectional (n = 73) and a longitudinal study (before, at 3, 6(More)
Nasal septum perforation is an uncommon and not well known feature of lupus erythematosus (LE). In general, it occurs during exacerbations and in a context of systemic vasculitis. Very rarely it can be a presenting sign, accompanying more usual manifestations of LE. We report the case of a 30-year-old woman who presented with a 2-year history of painful,(More)
BACKGROUND Psoriasis vulgaris is associated with overweight/obesity and with increased C-reactive protein (CRP), tumour necrosis factor (TNF)-α, interleukin (IL)-6, leptin and resistin levels and decreased adiponectin levels. OBJECTIVES To understand the role/relationship of adipokines, as well as CRP, in a Portuguese psoriatic population, by assessing(More)
BACKGROUND Several cross-sectional studies have shown that different cytokines and growth factors are enhanced in psoriasis. OBJECTIVES We aimed to understand the role/relation of interleukin (IL)-22, IL-17, IL-23, IL-8, vascular endothelial growth factor (VEGF) and tumour necrosis factor (TNF)-α in psoriasis vulgaris, addressing their levels and changes(More)
BACKGROUND Dioctophyma renale is a large nematode distributed worldwide that may cause progressive and severe destruction of renal parenchyma. OBJECTIVES The present study aimed to evaluate pre- and post-operatively dogs submitted to right nephrectomy due to D. renale and to assess the histopathological damage of the removed kidney. ANIMALS AND METHODS(More)
BACKGROUND The first reports of the application of ultravioletA₁ (UVA₁) phototherapy for scleroderma go back only to 1995, but since then, several studies have proven its effectiveness in this disease. OBJECTIVES To evaluate the effectiveness of low-dose (35 J/cm(2) ) UVA(1) phototherapy in patients with scleroderma, trying to define the subgroups that(More)
BACKGROUND Psoriatic patients present with an increased frequency of cardiovascular events. OBJECTIVE To study the impact of psoriasis duration and therapy on traditional and new cardiovascular risk factors. STUDY DESIGN A longitudinal study performed between 2005 and the first trimester of 2008. Each patient was followed up for 12 weeks, and was(More)