Hugo A. M. Torres

1Rogério A. L. Sertié
1Mario J. A. Saad
1Vânia D’Almeida
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MicroRNAs (miRNAs) are a class of small (∼22 nucleotides) non-coding RNAs that post-transcriptionally regulate gene expression by interacting with target mRNAs. A majority of miRNAs is located within intronic or exonic regions of protein-coding genes (host genes), and increasing evidence suggests a functional relationship between these miRNAs and their host(More)
  • Marcelo A. Mori, Vicência Micheline Sales, Fabiana Louise Motta, Raphael Gomes Fonseca, Natalia Alenina, Dioze Guadagnini +13 others
  • 2012
BACKGROUND Kinins participate in the pathophysiology of obesity and type 2 diabetes by mechanisms which are not fully understood. Kinin B(1) receptor knockout mice (B(1) (-/-)) are leaner and exhibit improved insulin sensitivity. METHODOLOGY/PRINCIPAL FINDINGS Here we show that kinin B(1) receptors in adipocytes play a role in controlling whole body(More)
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