Hubert van den Bergh

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The first effective therapy for exudative macular degeneration (AMD) was Photodynamic Therapy (PDT). Diagnosis of the disease was to a large extent by fluorescein angiography (FA). Distinguishing between the leaky choroidal neovessels (CNV) associated with exudative AMD, and the polypoidal structures associated with Polypoidal Choroidal Vasculopathy (PCV)(More)
Exogenous administration of 5-aminolaevulinic acid (ALA) is becoming widely used to enhance the endogenous synthesis of protoporphyrin IX (PpIX) in photodynamic therapy (PDT) and fluorescence photodetection (PD). Recently, results have shown that the chemical modification of ALA into its more lipophilic esters circumvents limitations of ALA-induced PpIX(More)
Article history: Available online xxxx Keywords: Atmospheric boundary layer Raman lidar Water vapor a b s t r a c t A new multi-telescope scanning Raman lidar designed to measure the water vapor mixing ratio in the atmospheric boundary layer for a complete diurnal cycle with high resolution spatial (1.25 m) and temporal (1 s) resolutions is presented. The(More)
Water vapour has been measured from the International Scientific Station Jungfraujochcrowave radiometry and Raman lidar. The abundance of atmospheric water vapour between the planetary boundary layer and the upper stratosphere varies over more than 5 three orders of magnitude. The currently used measurement techniques are suited to determine the abundance(More)
In this study, we implemented the feedback system control (FSC.II) technique in order to selectively optimize a combination of ten targeted agents in the inhibition of cell viability in a renal cell carcinoma cell line (786-O). The FSC.II technique is based on using designed experiments to ideally sample the response surface of the cell to generate accurate(More)
Air pollution measurements are aimed at improving our understanding of the chemical properties of the atmosphere, addressing mainly three issues with very different space and time scales: • Measurement of critical or peak values of air pollutant in densely urbanized/industrialized sites. • Long term observation and trend analysis on air quality. •(More)
Cancer, when detected at an early stage, has a very good probability of being eradicated by surgery or radiotherapy. However, less aggressive treatments also tend to provide high rates of cure without the side effects of radical therapy. We report on the results of our clinical experience with photodynamic therapy (PDT) for the treatment of early carcinomas(More)
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