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Ape1 is an important redox protein, essential for specific cytokine‑induced signal transduction. Ape1 signaling is also important in regulating the growth of cancer cells, including colon cancer cells. The present study investigated whether Ape1 signaling plays a role in the regulation of colon cancer stem cell (CCSC) growth. The results showed that Ape1(More)
LIGHT is a cytokine belonging to the TNF family. This cytokine has been extensively defined in its role on T-cell regulation and dendritic cell maturation. It also exhibits the role in liver regeneration. We recently identified its role in regulation of hematopoietic stem cell differentiation. However, the question whether this cytokine regulates(More)
A novel strategy on particle swarm optimization is proposed to solve dynamic optimization problems, in which the data are obtained not once for all but one by one. The evolutionary states of the particle swarm are guided recursively by the proposed algorithm, according to the information achieved by the continuous data and the prior estimated knowledge on(More)
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