Multiplex polymerase chain reaction (PCR) has been widely utilized for high-throughput pathogen identification. Often, a dye is used to intercalate the amplified DNA fragments, and identifications of the pathogens are carried out by DNA melting curve analysis or gel electrophoresis. Integrating DNA amplification and identification is a logic path toward… (More)
Androgen receptor (AR) antagonist MDV3100 is the first therapeutic approach in treating castration-resistant prostate cancer (CRPC), but tumours frequently become drug resistant via multiple mechanisms including AR amplification and mutation. Here we identify the small molecule Ailanthone (AIL) as a potent inhibitor of both full-length AR (AR-FL) and… (More)
Multiple synchronous lung cancers (MSLCs) present a clinical dilemma as to whether individual tumours represent intrapulmonary metastases or independent tumours. In this study we analyse genomic profiles of 15 lung adenocarcinomas and one regional lymph node metastasis from 6 patients with MSLC. All 15 lung tumours demonstrate distinct genomic profiles,… (More)
— This paper briefly introduces the main ideas of machine translation (MT) technique, then discusses the application of MT to the China-America Digital Academic Library (CADAL).
This paper briefly introduces the main ideas of a sustainable development OCR system based on open architecture techniques and then describes the construction of an optical character recognition (OCR) center built on computer clusters, for the purpose of dynamically improving the recognition precision of the digitized texts of a million volumes of books… (More)