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- Huajun Zhao, Haiying Liu, +8 authors Jian Ding
- Cancer research
- 2006
Inhibitors of tumor angiogenesis and metastasis are increasingly emerging as promising agents for cancer therapy. Recently, heparanase inhibitors have offered a new avenue for such work because… (More)
- Huajun Zhao, Po-Chun Ho, +4 authors Shao-Chun Wang
- PloS one
- 2012
Cell proliferation in primary and metastatic tumors is a fundamental characteristic of advanced breast cancer. Further understanding of the mechanism underlying enhanced cell growth will be important… (More)
- Huajun Zhao, Yuan-Hung Lo, Ling Yu, Shao-Chun Wang
- Molecular carcinogenesis
- 2011
Inhibiting estrogen receptor (ER) function with specific estrogen receptor modulators (SERM) can achieve a primary response in cancer patients; however, intrinsic or subsequently acquired resistance… (More)
- Huajun Zhao, Fu Ou-Yang, +9 authors Shao-Chun Wang
- Neoplasia
- 2010
Targeting the estrogen receptor is an important strategy in breast cancer therapy. However, although inhibiting estrogen receptor function with specific estrogen receptor modulators can achieve a… (More)
- Yuan-Hung Lo, Po-Chun Ho, Huajun Zhao, Shao-Chun Wang
- Anticancer research
- 2011
BACKGROUND
The dual kinase inhibitor lapatinib (Tykerb) has been applied for advanced breast cancer. However, the effectiveness in the clinic has been elusive and the development of novel approaches… (More)
- Chenghua Lou, Zhihui Zhu, Yaping Zhao, Rui Feng Zhu, Huajun Zhao
- Oncology reports
- 2017
Arctigenin is a bioactive lignan isolated from the seeds of Arctium lappa L. which has been widely used as a diuretic and a diaphoretic in Traditional Chinese Medicine. In the present study, the… (More)
- Bo Yang, Rui Feng Zhu, Shasha Tian, Yiqi Wang, Siyue Lou, Huajun Zhao
- Biomedicine & pharmacotherapy = Biomedecine…
- 2017
Jatamanvaltrate P is a novel iridoid ester isolated from Valeriana jatamansi Jones, a traditional medicine used to treat nervous disorders. In this study, we found that Jatamanvaltrate P possessed… (More)
- Ang Lin, Guan Wang, +5 authors Jian Zhang
- Oncoimmunology
- 2016
Toll-like receptors (TLRs) can be expressed by tumor cells, and each TLR exhibits different biological functions. Evidences showed the activation of some certain TLRs could promote tumor progression.… (More)
- Huajun Zhao, Yuan-Hung Lo, +4 authors Shao-Chun Wang
- Molecular cancer therapeutics
- 2011
The proliferation cell nuclear antigen (PCNA) is a critical protein required for DNA replication in proliferating cells including cancer cells. However, direct inhibition of PCNA in cancer cells has… (More)
- Xuefen Tao, Yongmin Ma, Jing Chen, Huajun Zhao
- Natural product communications
- 2015
A series of caudatin ester derivatives were synthesized and tested for their activities against human lung cancer A549, human prostate cancer PC3, human liver cancer BEL-7402 and human gastric cancer… (More)