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Ruthenium(II) anthraquinone complexes as two-photon luminescent probes for cycling hypoxia imaging in vivo.
- Pingyu Zhang, Huaiyi Huang, Y. Chen, Jin-quan Wang, L. Ji, H. Chao
- Biology, Medicine
- 1 June 2015
Recently, cycling hypoxia, with cycles of hypoxia followed by reoxygenation, was found to induce the up-regulation of HIF-1 activity in tumor cells and reduce the success rate of radiotherapy or… Expand
Synthesis, characterization and biological evaluation of mixed-ligand ruthenium(II) complexes for photodynamic therapy.
- Huaiyi Huang, Pingyu Zhang, Bole Yu, Chengzhi Jin, L. Ji, H. Chao
- Chemistry, Medicine
- Dalton transactions
- 29 September 2015
This study investigated the photodynamic therapy (PDT) and anticancer activity of mixed ligand Ru(ii) terpyridyl complexes (Ru1-Ru3). The photophysical and photochemical properties, hydrophobic… Expand
Future potential of osmium complexes as anticancer drug candidates, photosensitizers and organelle-targeted probes.
Recent work has shown that the chemical reactivity of osmium complexes can be finely tuned by the choice of osmium oxidation state, the ligands (including C- and N-bound), and the coordination… Expand
TagBooth: Deep shopping data acquisition powered by RFID tags
- Tianci Liu, L. Yang, X. Li, Huaiyi Huang, Y. Liu
- Computer Science
- IEEE Conference on Computer Communications…
- 24 August 2015
To stay competitive, plenty of data mining techniques have been introduced to help stores better understand consumers' behaviors. Expand
Highly Charged Ruthenium(II) Polypyridyl Complexes as Lysosome-Localized Photosensitizers for Two-Photon Photodynamic Therapy.
Photodynamic therapy (PDT) is a noninvasive medical technique that has received increasing attention over the last years and been applied for the treatment of certain types of cancer. However, the… Expand
Targeting nucleus DNA with a cyclometalated dipyridophenazineruthenium(II) complex.
- Huaiyi Huang, Pingyu Zhang, +4 authors H. Chao
- Chemistry, Medicine
- Journal of medicinal chemistry
- 23 October 2014
Recently, coordinatively saturated and substitutionally inert Ru(II) complexes have been investigated as anticancer agents. Herein a cyclometalated Ru(II) complex, [Ru(bpy)(phpy)(dppz)](+), was found… Expand
Comparison between polypyridyl and cyclometalated ruthenium(II) complexes: anticancer activities against 2D and 3D cancer models.
The aim of this study was to illustrate the dramatically different anticancer activities between coordinatively saturated polypyridyl (1 a-4 a) and cyclometalated (1 b-4 b) ruthenium(II) complexes.… Expand
Noncovalent Ruthenium(II) Complexes-Single-Walled Carbon Nanotube Composites for Bimodal Photothermal and Photodynamic Therapy with Near-Infrared Irradiation.
- Pingyu Zhang, Huaiyi Huang, +6 authors H. Chao
- Materials Science, Medicine
- ACS applied materials & interfaces
- 8 October 2015
To enhance the efficacy and optimize the treatment of cancers, the integration of multimodal treatment strategies leading to synergistic effects is a promising approach. The coassembly of… Expand
Ruthenium(II) Complexes with 2-Phenylimidazo[4,5-f][1,10]phenanthroline Derivatives that Strongly Combat Cisplatin-Resistant Tumor Cells
Cisplatin was the first metal-based therapeutic agent approved for the treatment of human cancers, but its clinical activity is greatly limited by tumor drug resistance. This work utilized the parent… Expand
Extending the Excitation Wavelength of Potential Photosensitizers via Appendage of a Kinetically Stable Terbium(III) Macrocyclic Complex for Applications in Photodynamic Therapy.
The development of viable photodynamic therapy protocols is often hindered by photosensitizers that require high-energy UV irradiation that has limited potential for clinical use due to its low… Expand