Huaihong Zhang

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BACKGROUND Few data are available regarding the use of tenofovir disoproxil fumarate (TDF) during pregnancy for the prevention of mother-to-child transmission of hepatitis B virus (HBV). METHODS In this trial, we included 200 mothers who were positive for hepatitis B e antigen (HBeAg) and who had an HBV DNA level higher than 200,000 IU per milliliter.(More)
To enhance site-specific intracellular delivery against the folate receptor, a drug carrier was designed and synthesized by bioconjugation of folic acid (FA) to β-cyclodextrins (β-CD) through a poly(ethylene glycol) (PEG) spacer from "click chemistry" strategy. The resulted conjugates were confirmed by (1)H NMR and IR spectroscopy. Host-guest interactions(More)
In the title complex, [Cu(C(14)H(13)N(2)O(2))(2)], the Cu(II) ion is located on a crystallographic inversion center. The complex thus adopts a square-planar trans-[CuN(2)O(2)] coordination geometry, with the Cu(II) ion coordinated by two 2-meth-oxy-6-(3-pyridylmethyl-imino-meth-yl)phenolate (Schiff base) ligands. The aryl and pyridyl rings in the Schiff(More)
In the title mononuclear complex, [Cu(C(13)H(10)ClN(2)O)(H(2)O)]-NO(3)·H(2)O, the Cu(II) atom is four-coordinated by two N atoms and one O atom of the tridentate Schiff base ligand and one O atom from the coordinated water mol-ecule in a slightly distorted square-planar configuration. The nitrate ion inter-acts with the copper center [Cu1⋯O3 = 2.579 (4) Å].(More)
A blue-emitting organic compound, 9-hydroxyl-3-hydroxyethyl-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one (I), was synthesized by the reaction of 2-amino-3-hydroxylpridine with 2-acetylbutyrolactone. The crystal of the title compound in larger size was reported for the first time through the slow evaporation method. The whole molecule in the crystal is(More)
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