Hua-rong Hong

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OBJECTIVE To clarify the changes in cell proliferation, differentiation, apoptosis and in the expression of vital cytokines during development of 6-8 week old embryo, and hence provide the evidence for identifying the mechanisms of cell proliferation, differentiation, apoptosis during early developing human embryonic brain. METHODS Human aborted embryos(More)
OBJECTIVE To investigate the function of HNF4a and HNF6 during liver development. METHODS The expression levels of HNF4alpha and HNF6 at E8, 9, 13, 15, 17, P1 and in adult mouse liver were detected by RT-PCR and in situ hybridization. RESULTS RT-PCR results showed that HNF4alpha first expressed at E9, the time of liver bud formation, and lasted through(More)
The aim was to study the expression of VEGF-A, VEGF-C, angiopoietin-1, angiopoietin-2 and their receptors on development liver during gestation of weeks 3-12 of human embryo. Human embryo contingently aborted at 3-12 weeks of gestation were collected with signed agreements of the pregnant women suffered from accidental abortions. The specimens were fixed by(More)
The present study examined whether a single or multiple episode(s) of status epilepticus induced with kainic acid (KA) during the first 3 weeks of postnatal (P) development would aberrantly stimulate proliferation zones that alters migration to potentially injured areas and whether they would be blocked by selective Group I mGluR antagonists. mGluR1α(More)
The study was to investigate the expression of VEGFA, VEGFC, angiopoietin-1, angiopoietin-2 and their receptors on yolk sac blood island, AGM region during gestation of 3th-12th weeks of human embryo. Human embryo contingently aborted at 3 - 12 weeks of gestation were collected with signed agreements of the pregnant women suffered from accidental abortions.(More)
OBJECTIVES To study the expression of CD34, CD31, CD14, CD10 and factor VIII on blood island of yolk sac (YS), PAS/aorta-germen-mesonephros (AGM) region and hepatic hematopoietic foci. METHODS Thirty-two cases of 3rd-12th weeks human embryo were obtained by drug abortion. Paraffin embedded sections with H.E staining and immunohistochemistry reaction(More)
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