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Fuzzy clustering is capable of finding vague boundaries that crisp clustering fails to obtain. But time complexity of fuzzy clustering is usually high, and the need to specify complicated parameters hinders its use. In this paper, an entropy-based fuzzy clustering method is proposed. It automatically identifies the number and initial locations of cluster(More)
Infection of the stomach by Helicobacter pylori is ubiquitous among humans. However, although H. pylori strains from different geographic areas are associated with clear phylogeographic differentiation, the age of an association between these bacteria with humans remains highly controversial. Here we show, using sequences from a large data set of bacterial(More)
We consider how two secondary users should interact to maximize their total throughput in a two- channel sensing-based opportunistic spectrum access network where spectrum opportunities are time varying and spatially inhomogeneous. By modeling the occupancy of the primary users as discrete-time Markov chains, we obtain the optimal dynamic coordination(More)
Currently available genetic and archaeological evidence is generally interpreted as supportive of a recent single origin of modern humans in East Africa. However, this is where the near consensus on human settlement history ends, and considerable uncertainty clouds any more detailed aspect of human colonization history. Here, we present a dynamic genetic(More)
BACKGROUND Prognosis of patients with gastric cancer (GC) is generally poor due to the lack of non-invasive tools for GC detection. The purpose of present study was to identify a serum microRNA (miRNA) expression profile that can serve as a novel diagnostic biomarker for GC detection and to assess its clinical applications in monitoring disease progression.(More)
Accurate inferences on population genetics data require a sound underlying theoretical null model. Organisms alternating sexual and asexual reproduction during their life-cycle have been largely neglected in theoretical population genetic models, thus limiting the biological interpretation of population genetics parameters measured in natural populations.(More)
Reactive oxygen metabolites are important mediators in cisplatin-induced apoptosis in renal tubular epithelial cells (LLC-PK1). Mitochondria have been implicated to play a principal role in cisplatin-induced apoptosis. Caspase 12, an endoplasmic reticulum (ER)-specific caspase, participates in apoptosis under ER stress. Cytochrome P450 system is crucial to(More)
BACKGROUND AND PURPOSE A large number of traditional Chinese patent medicine (TCPM) are widely used for ischemic stroke in China. The aim of this study was to systematically review the existing clinical evidence on TCPM for ischemic stroke. METHODS We identified all TCPM that were listed in the Chinese National Essential Drug list of 2004 and those(More)
Law enforcement agencies need crime forecasts to support their tactical operations; namely, predicted crime locations for next week based on data from the previous week. Current practice simply assumes that spatial clusters of crimes or ‘‘hot spots’’ observed in the previous week will persist to the next week. This paper introduces a multivariate prediction(More)