Hua Guo Zhang

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Mixed-lineage kinase 3 (MLK3) is a mitogen-activated protein kinase (MAPK) kinase kinase that activates MAPK pathways, including the c-Jun NH(2)-terminal kinase (JNK) and p38 pathways. MLK3 and its family members have been implicated in JNK-mediated apoptosis. A survey of human cell lines revealed high levels of MLK3 in breast cancer cells. To learn more(More)
Blind despreading of long-code direct sequence spread spectrum (DS-SS) signal with unknown carrier frequency offset (CFO) is considered. The maximum likelihood estimate (MLE) of spreading waveform is first derived, and to cope with the unknown CFO, we then use the semidefinite relaxation (SDR) technique to approximate our MLE problem as a convex(More)
MLK3 (mixed lineage kinase 3) is a MAP3K [MAPK (mitogen-activated protein kinase) kinase kinase] that activates multiple MAPK pathways, including the JNK (c-Jun N-terminal kinase) pathway. Immunoblotting of lysates from cells ectopically expressing active MLK3 revealed an additional immunoreactive band corresponding to a CTF (C-terminal fragment) of MLK3.(More)
In non-cooperative scenarios, the estimation of direct sequence spread spectrum (DS-SS) signals has to be done in a blind manner. In this letter, we consider the spreading sequence estimation problem for DS-SS signals. First, the maximum likelihood estimate (MLE) of spreading sequence is derived, then a semidefinite relaxation (SDR) approach is proposed to(More)
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