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Anti-inflammatory endiandric acid analogues from the roots of Beilschmiedia tsangii.
TLDR
Bioassay-guided fractionation of roots of Beilschmiedia tsangii led to the isolation of six new endiandric acid analogues, which exhibited potent iNOS inhibitory activity and were determined by spectroscopic techniques.
Costunolide causes mitotic arrest and enhances radiosensitivity in human hepatocellular carcinoma cells
TLDR
Investigating the effect of costunolide, a sesquiterpene lactone isolated from Michelia compressa, on cell cycle distribution and radiosensitivity of human hepatocellular carcinoma (HCC) cells shows it could reduce the viability and arrest cell cycling at mitosis in hepatoma cells.
Secondary Metabolites from the Roots of Beilschmiedia tsangii and Their Anti-Inflammatory Activities
TLDR
Four new endiandric acid analogues and two new sesquiterpenes were isolated from the roots of Beilschmiedia tsangii (Lauraceae), together with four known compounds, and exhibited moderate iNOS inhibitory activity.
Secondary metabolites from the roots of Neolitsea daibuensis and their anti-inflammatory activity.
Bioassay-guided fractionation of the roots of Neolitsea daibuensis afforded three new β-carboline alkaloids, daibucarbolines A-C (1-3), three new sesquiterpenoids, daibulactones A and B (4 and 5) and
Six new metabolites produced by Colletotrichum aotearoa 09F0161, an endophytic fungus isolated from Bredia oldhamii
TLDR
This is the first report on isochroman glycoside metabolites (1–4) from the genus Colletotrichum, and the effects of some isolates on the inhibition of nitric oxide (NO) production in lipopolysaccharide-activated murine macrophage RAW2647 cells were evaluated.
Avocado (Persea americana) fruit extract (2R,4R)-1,2,4-trihydroxyheptadec-16-yne inhibits dengue virus replication via upregulation of NF-κB–dependent induction of antiviral interferon responses
TLDR
It is demonstrated that a natural product, extracted from avocado (Persea americana) fruit, can inhibit DENV-2 replication in a concentration-dependent manner and efficiently suppresses replication of all DENV serotypes.
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