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MOTIVATION Cancer development is a complex and heterogeneous process. It is estimated that 5-10% of human genes probably contribute to oncogenesis, whereas current experimentally validated cancer genes only cover 1% of the human genome. Thus hundreds of cancer genes may still remain to be identified. To search for new genes that play roles in carcinogenesis(More)
The low-copy repeat (LCR) is a new class of repetitive DNA element and has been implicated in many human disorders, including DiGeorge/velocardiofacial syndrome (DGS/VCFS). It is now recognized that nonallelic homologous recombination (NAHR) through LCRs flanking the chromosome 22q11.2 region leads to genome rearrangements and results in the DGS/VCFS. To(More)
This paper proposes a high step-up solar power optimizer (SPO) that efficiently harvests maximum energy from a photovoltaic (PV) panel then outputs energy to a dc-microgrid. Its structure integrates coupled inductor and switched capacitor technologies to realize high step-up voltage gain. The leakage inductance energy of the coupled inductor can be recycled(More)
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