Hsi-Chin Wu

Tzer-Bin Lin7
Hsien-Yu Peng7
7Tzer-Bin Lin
7Hsien-Yu Peng
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In recent years, the utilization of nanomaterials such as carbon nanotubes (CNTs) in the field of neuroscience has forever changed the approach to nerve-related research. The array of novel properties CNTs possess allows them to interact with neurons at the nanodimensional scale. In this study, a CNT rope substrate is developed to allow the electrical(More)
BACKGROUND Studies on the association between prostate cancer and cadmium exposure have yielded conflicting results. This study explored cadmium burden on the risk and phenotype of prostate cancer in men with no evident environmental exposure. METHODS Hospital-based 261 prostate cancer cases and 267 controls with benign diseases were recruited from four(More)
OBJECTIVE We assessed the measurement equivalence and feasibility of the paper-and-pencil and touch-screen modes of administration of the Taiwan Chinese version of the EORTC QLQ-PR25, a commonly used questionnaire to evaluate the health-related quality of life (HRQOL) in patients with prostate cancer in Taiwan. METHODS A cross-over design study was(More)
Current therapeutic regimen in prostate cancer Prostate cancer (PCa) is the lead malignancy among males in Western countries, accounting for 28% (238,590) of newly diagnosed cancers in United States in 2013 [1]. It has been the second common cause of cancer deaths in men (behind lung cancer) for two decades [1, 2]. Treatment for clinically localized PCa(More)
BACKGROUND A real-time clinical decision support system (RTCDSS) with interactive diagrams enables clinicians to instantly and efficiently track patients' clinical records (PCRs) and improve their quality of clinical care. We propose a RTCDSS to process online clinical informatics from multiple databases for clinical decision making in the treatment of(More)
OBJECTIVE To evaluate the psychometric properties of the Taiwan Chinese Version of the EORTC QLQ-PR25 health-related quality of life (HRQOL) questionnaire for patients with prostate cancer. METHODS 135 prostate cancer patients were recruited in the urology outpatient clinic of a university teaching hospital. Each patient completed the EORTC QLQ-PR25 at(More)
OBJECTIVE The aim of this study was to establish a real time online health and decision support system with the novel information technology integrating modelized architecture and Web services for clinical infometrics on patient reported outcome (PRO) and quality of life (QOL) for prostate cancer patients. METHODS The patient-oriented interface was(More)
BACKGROUND Intracellular redistribution of α-amino-3-hydroxy-5-methyl-4-isoxazoleproprionate receptors (AMPARs) is known to be induced by natural painful stimulation. We tested the hypothesis that that protein kinase A (PKA)-dependent AMPAR trafficking underlies the development of N-methyl-d-aspartate receptor-mediated cross-organ sensitization in vivo. (More)
To determine the role of 17beta-estradiol and involvement of intracellular phosphatidylinositol-3-kinase signaling in cross-organ sensitization between the descending colon and the urethra, we analyzed urethra reflex activity and protein expressions in lumbosacral (L6-S2) spinal dorsal horn in response to mustard oil instillation into the descending colon(More)
To clarify the role of descending dopaminergic innervation in reflexive urethral closure, the impacts of dopaminergic D2 receptor (DR2)-selective agonists and antagonists on repetitive stimulation-induced pelvic-to-urethra spinal reflex potentiation (SRP) were tested using in vivo rat preparations. Pelvic afferent nerve test stimulation (TS; 1 pulse/30 s(More)