Howard Leung

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Kaposi's sarcoma (KS), a multifocal vascular neoplasm linked to human herpesvirus-8 (HHV-8/KS-associated herpesvirus [KSHV]) infection, is the most common AIDS-associated malignancy. Clinical management of KS has proven to be challenging because of its prevalence in immunosuppressed patients and its unique vascular and inflammatory nature that is sustained(More)
Membrane protein plays an important role in some biochemical process such as signal transduction, transmembrane transport, etc. Membrane proteins are usually classified into five types [Chou, K.C., Elrod, D.W., 1999. Prediction of membrane protein types and subcellular locations. Proteins: Struct. Funct. Genet. 34, 137-153] or six types [Chou, K.C., Cai,(More)
In this paper, we propose a new method for biped humanoids to compensate for large amounts of angular momentum induced by strong external perturbations applied to the body during gait motion. Such angular momentum can easily cause the humanoid to fall down onto the ground. We use an Angular Momentum inducing inverted Pendulum Model (AMPM), which is an(More)
Evaluating the similarity of motions is useful for motion retrieval, motion blending, and performance analysis of dancers and athletes. Euclidean distance between corresponding joints has been widely adopted in measuring similarity of postures and hence motions. However, such a measure does not necessarily conform to the human perception of motion(More)
A system that can retrieve logically relevant 3D captured motions is useful in game and animation production. We presented a robust logical relevance metric based on the relative distances among the joints. Existing methods select a universal subset of features for all kinds of queries which may not well characterize the variations in different queries. To(More)
We build a distance education application of a Chinese handwriting education system that allows students to do practice at anytime and anywhere. As an intelligent tutor, the system can automatically check the handwriting errors, such as the stroke production errors, stroke sequence error and stroke relationship error. Then our system should provide useful(More)
Anthrax lethal toxin (LT), a virulence factor secreted by Bacillus anthracis, is selectively toxic to human melanomas with the BRAF V600E activating mutation because of its proteolytic activities toward the mitogen-activated protein kinase kinases (MEKs). To develop LT variants with lower in vivo toxicity and high tumor specificity, and therefore greater(More)
In this paper, an objective assessment for determining whether a person has Parkinson disease is proposed. This is achieved by analyzing the correlation between joint movements, since Parkinsonian patients often have trouble coordinating different joints in a movement. Thus, the auto-correlation coefficient of single joint movements and the(More)
In this paper, a new dance training system based on the motion capture and virtual reality (VR) technologies is proposed. Our system is inspired by the traditional way to learn new movements—imitating the teacher’s movements and listening to the teacher’s feedback. A prototype of our proposed system is implemented, in which a student can imitate the motion(More)