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Carcinoma of the tongue is the second most common malignancy of the oral cavity, predominantly affecting males in the sixth and seventh decades of life. The risk factors for this disease (primarily tobacco and ethanol abuse) are well documented in the literature. The current five-year survival for a T1 lesion without nodal involvement is approximately 80%.(More)
Gustatory sweating, also known as Frey's syndrome, is a recognized phenomenon after parotidectomy. The incidence of clinically significant gustatory sweating may be dependent on the thickness of the skin flap that is elevated at the time of surgery. Dissection in the subcutaneous level or the deeper sub-superficial musculoaponeurotic system level are 2(More)
In Canada, hydroxyethyl starch 264/0.45 (HES 264/0.45; molar weight 264 kDa, molar substitution 0.45) has largely replaced albumin as the colloidal fluid of choice for perioperative intravascular volume expansion. The maximum recommended dose of HES 264/0.45 is 28 mL/kg; however, there are no clinical data supporting this limit. In this study we compared(More)
Epithelial-myoepithelial carcinoma of salivary gland is a rare tumor only recently described in the English language literature. This paper adds four new cases to the 30 which have previously been reported. The clinical presentation of this unusual neoplasm is documented in the accompanying case reports and the appropriate surgical management outlined.(More)
BACKGROUND Dermoid cyst of the floor of the mouth is a rare, benign lesion requiring surgical intervention. To our knowledge, the preoperative diagnosis of this entity by fine needle aspiration (FNA) cytology has not been previously reported in the cytologic literature. CASE The patient presented with a massive swelling of the floor of the mouth that(More)
The use of flow cytometry to measure the DNA content from tumors has evolved over the years. In squamous cell carcinoma arising in the head and neck, there has not been uniform agreement in the literature, and decisions regarding patient treatment cannot be made using this parameter. The use of proliferating cell nuclear antigen (PCNA), a newly available(More)
The flow cytometer is capable of analyzing a large number of cells or cell nuclei. The flow cytometer has been used to analyze the DNA content of tumor cells from squamous cell carcinomas of the upper aerodigestive tract using a modification of the Vindelov staining procedure. The main difficulty in analyzing solid tumors using flow cytometry technology is(More)
Ionizing radiation is an important treatment modality in the management of head and neck squamous cell carcinoma. The superoxide (O2-) and hydroxyl (OH.) radicals produced from oxygen and the radio-hydrolysis of water are responsible for most of the DNA and lipid membrane injury caused by radiotherapy. Superoxide dismutase (SOD) and catalase (CAT) are(More)
Three hundred forty-two cases of laryngeal cancer were treated at the University of Michigan, Ann Arbor. One hundred ten supraglottic cancers and 150 glottic cancers were studied in depth. Conservation surgery was performed on 63 patients. Determinate two-year disease-free survival for glottic cancer was 90% in those irradiated primarily, 83% for those(More)
OBJECTIVE The aim of this study was to expand the rigour and scope of soft-tissue finite-element modelling through the introduction of nonlinear biomechanics. The capability to simulate "tissue" movement in three-dimensional space was a priority. METHOD A computer-based finite-element technique was used to approximate the exact solution to the governing(More)