Houda Benhelli-Mokrani

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High-density nanoarchitectures, endowed with simultaneous fluorescence and contrast properties for MRI and TEM imaging, have been obtained using a simple self-assembling strategy based on supramolecular interactions between non-doped fluorescent organic nanoparticles (FON) and superparamagnetic nanoparticles. In this way, a high-payload core-shell structure(More)
Fluorescent organic nanoparticles (FONs), made of self-assembled solvatochromic fluorophores, represent a novel class of bright imaging agents. On page 2727, E. Ishow and co-workers show how in cellulo studies evidence dramatic dissembling of FONs by macrophages compared to cancer cells. Macrophages disintegrate internalized yellow-emitting FONs and expulse(More)
Strongly solvatochromic fluorophores are devised, containing alkyl chains and enable to self-assemble as very bright fluorescent organic nanoparticles (FONs) in water (Φf = 0.28). The alkyl chains impart each fluorophore with strongly hydrophobic surroundings, causing distinct emission colors between FONs where the fluorophores are associated, and their(More)
The expression and activity of DNA-dependent protein kinase (DNA-PK) is related to DNA repair status in the response of cells to exogenous and endogenous factors. Recent studies indicate that Epidermal Growth Factor Receptor (EGFR) is involved in modulating DNA-PK. It has been shown that a compound(More)
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