Learn More
The accuracy of the vast amount of genotypic information generated by high-throughput genotyping technologies is crucial in haplotype analyses and linkage-disequilibrium mapping for complex diseases. To date, most automated programs lack quality measures for the allele calls; therefore, human interventions, which are both labor intensive and error prone,(More)
The Chandra X-Ray Observatory, launched by the space shuttle Columbia in July 1999, has taken its place with the Hubble Space Telescope, the Compton Gamma Ray Observatory and the Spitzer Infrared Space Telescope in NASA’s fleet of state of the art space-based Great Observatories. As the world’s premier X-ray observatory, Chandra gives astronomers a powerful(More)
In recent years, there has been an avalanche of new data in observational high-energy astrophysics. Recently launched or soon-to-be launched spacebased telescopes that are designed to detect and map ultra-violet, X-ray, and γ-ray electromagnetic emission are opening a whole new window to study the cosmos. Because the production of high-energy(More)
We would like to thank Professor Loh and Professor Gelman for their thoughtful comments. Some of the detailed points that the discussants bring up remind us to emphasize that in many regards our article offers only an overview of the scientific questions we aim to address and of the methods, models, and algorithms that we employ. Some technical details are(More)
We develop a powerful new method to reconstruct stellar Differential Emission Measures (DEMs), whose Bayesian framework allows us to incorporate atomic and calibration errors as prior information. For instance, known errors in the line locations, as well as missing lines with only minimal information, can be included directly during fitting. Highly(More)
Marginal Data Augmentation and Parameter-Expanded Data Augmentation are related methods for improving the the convergence properties of the two-step Gibbs sampler know as the Data Augmentation sampler. These methods expand the parameter space with a so-callled working parameter that is unidentifiable given the observed data but is identifiable given the(More)
  • 1