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Most studies of continuous EEG data have used frequency transformation, which allows the quantification of brain states that vary over seconds. For the analysis of shorter, transient EEG events, it is possible to identify and quantify brain electric microstates as subsecond time epochs with stable field topography. These microstates may correspond to basic(More)
Modern mobile phones emit electromagnetic fields (EMF) ranging from 900 to 2000 MHz which are suggested to have an influence on well-being, attention and neurological parameters in mobile phone users. Until now most studies have investigated Global System for Mobile Communications (GSM)-EMF and only very few studies have focused on Universal Mobile(More)
The aim of this study was to search for differences in the EEG of first-episode, drug-naive patients having a schizophrenic syndrome which presented different time courses in response to antipsychotic treatment. Thirteen patients who fulfilled DSM-IV diagnosis for schizophrenia or schizophreniform disorder participated in this study. Before beginning(More)
Approximately 20% of Charles River rats which were chronically implanted with brain electrodes for EEG recordings exhibited within half a year of the implantation spontaneous, paroxysmally occurring, steep EEG potentials of high amplitude (spikes and waves) whilst falling asleep. These EEG paroxysms were dose dependently antagonized by the 'petit mal' drugs(More)
The characteristics of the power density spectra of the frontal and occipital cortical EEG between 1 and 31 Hz as well as the total power of the neck muscle EMG during an 8-second epoch were used to differentiate 8 vigilance stages in normal rats. The following stages and the time spent within these stages during a 6-hour recording (9.00-15.00) were(More)
RATIONALE Olanzapine is an atypical antipsychotic drug with a more favourable safety profile than typical antipsychotics with a hitherto unknown topographic quantitative electroencephalogram (QEEG) profile. OBJECTIVES We investigated electrical brain activity (QEEG and cognitive event related potentials, ERPs) in healthy subjects who received olanzapine.(More)
Based on an integrative brain model which focuses on memory-driven and EEG state-dependent information processing for the organisation of behaviour, we used the developmental changes of the awake EEG to further investigate the hypothesis that neurodevelopmental abnormalities (deviations in organisation and reorganisation of cortico-cortical connectivity(More)
The sleep-waking pattern of the isolated female rat showed a clear ultra-, circa- and infradian vigilance rhythm. The ultradian period was about 4-6 h. During the day, the amount of slow wave sleep (SWS) decreased and that of paradoxical sleep (PS) increased. In general, desynchronisation of the EEG increased during the day. The circadian period was(More)
In order to gain a better understanding of the role of the noradrenergic system in the control of the EEG sleep-waking stages, the effects of the selective alpha 1-antagonist prazosin was investigated in the rat. Oral doses of prazosin (0.1-10 mg/kg) were administered that have been shown to enter the brain. EEG sleep and waking stages were recorded either(More)
Patients with schizophrenia have reduced execution functions and white matter alterations indicating cerebral disconnectivity. Here we investigated the relationship between white matter integrity and event related potentials (ERP) during a continuous performance test (CPT). Anisotropy values were correlated with the brain electrical P300 microstate duration(More)