Horst-Ernst Beckmann

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The urinary excretion of the norepinephrine metabolite 3-methoxy-4-hydroxyphenylglycol (MHPG) was measured in unipolar depressed patients before and during the fourth week of treatment with either imipramine hydrocloride or amitriptyline hydroxhloride. On the basis of strict rating criteria, 24 patients were selected as either unequivocal responders or(More)
3-Methoxy-4-hydroxyphenylglycol (MHPG), the urinary metabolite thought best to reflect brain norepinephrine metabolism, was studied in a large group of hospitalized depressed patients with primary affective disorder and in normal controls, as part of an ongoing effort to evaluate the role of central amine dysfunction in affective illness. Overall there was(More)
The changes in the peripheral nerve function of three patients with chronic renal failure who were treated over a period of 1-1/2 to 2 years by hemofiltration have been analyzed in the form of a longitudinal study by quantitative measurements of vibratory perception threshold and nerve conduction velocity. Changes in vibratory perception threshold were(More)
Autopsy findings and examination of histological sections from 12 schizophrenic patients and from age-matched, non-schizophrenic controls were enlarged and confirmed our previous study. Four subgroups were differentiated with gross abnormalities, in most cases with asymmetry of the temporal sulcal gyral pattern. Two types of macroscopical deviations are(More)
In recent years neuroimaging techniques have revealed various cerebral and structural variances in patients with schizophrenic psychoses. The best established findings are the enlargement of the lateral ventricles and discrete structural deficits in temporobasal structures of the cortex. Neuropathological investigations have detected subcortical as well as(More)
This study attempted to clarify sources of artefact in biochemical studies with affective disorders in which 3-methoxy-4-hydroxy phenylglycol (MHPG) is used as a measurement of change in central nervous system norepinephrine (NE) turnover. Substantial increases in urinary MHPG excretion occurred in ten of the 11 patients when they increased their level of(More)
Anatomie und Geometrie der Karotisgabel sind sehr komplex. Mediale und ventromediale Lagevariationen der ACI werden in der Literatur mit bis zu 6% angegeben. Damit sind sie nicht selten genug, um bei der Karotisdesobliteration nicht angetroffen zu werden. Ein Einfluss solcher Lagevariationen auf das chirurgische Vorgehen wurde bisher nicht beschrieben. Erst(More)
It was to be investigated whether the elimination rate of 14-hydroxy-3beta-[(4-O-methyl-alpha-L-rhamnopyranosyl)oxy]-14beta-bufa-4,20,22-trienolide (meproscillarin, Clift) is influenced by the renal function after discontinuance of long-term application. A group of 9 patients with renal insufficiency of varying extent associated with heart failure received(More)