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BACKGROUND The aim of this study was to investigate whether an increase in malignancy level is accompanied by significant modifications of the expression of galectin-1, galectin-3, and Thomsen-Friedenreich antigen (T antigen) as well as the expression of binding sites for these three markers in head and neck squamous cell carcinomas (HNSCCs). METHODS(More)
BACKGROUND Histopathologic grading and clinical staging cannot provide a precise prognosis of oral cavity cancer patients. The use of glycohistochemical markers may improve the level of prognostic accuracy of such conventional classification systems. METHODS Computer-assisted microscopy was employed in a series of 40 oral cavity cancers to determine(More)
The accurate determination of levels of differentiation is of prognostic value in human head and neck squamous cell carcinomas (HNSCCs). Because the deliberate selection of biochemical determinants accompanying certain stages of differentiation can refine the predictive power of histochemical assessments, the application of the quantitative evaluation of(More)
The authors report a first case of chronic motor axonal neuropathy involving ENT manifestations, in a 64-year-old male presenting with gait difficulties, effort dyspnoea and dysphonia. Eleven months after the first symptoms, he developed severe hypoventilation, limb weakness and bilateral vocal fold palsy and had to be intubated for respiratory failure. The(More)
Disinhibition refers to a stimulus-elicited recovery of a conditioned response (CR) that had undergone nonreinforcement over a series of extinction trials or in connection with conditioned inhibition training. This dissertation reports attempts to demonstrate disinhibition of the conditioned nictitating membrane response of the rabbit. Disinhibition differs(More)