Hoonsung Choi

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BACKGROUND Recent reports suggest that mutations in the promoter of the gene encoding telomerase reverse transcriptase (TERT) affect thyroid cancer outcomes. METHODS In all, 551 patients with differentiated thyroid cancer (DTC) enrolled in this study. The median follow-up duration was 4.8 years (interquartile range, 3.4-10.6 years). RESULTS TERT(More)
T he prevalence of diabetes in South Korea reached 9 to ;10% in adults aged $30 years and remained stable in the 2000s (1,2). Even though the Korean population is rapidly aging, the proportion of the elderly population aged $65 years has been increasing over the past 10 years from 7.2% of the total population in 2000 to 11.0% in 2010 (3). We investigated(More)
OBJECTIVE With the recent increasing rates of screening for thyroid cancer, the cancers now tend to be smaller and less aggressive than those that are diagnosed when presented with symptoms, suggesting changes in the clinical validity of conventional prognostic factors for outcomes. We performed the retrospective study to identify the secular trends in the(More)
CONTEXT Large-sample studies with long-term follow-up data are limited for pediatric patients with thyroid cancer. OBJECTIVE Secular changes in clinicopathological characteristics and outcomes in pediatric patients with thyroid cancer were investigated and compared with those of adults. DESIGN AND PATIENTS A retrospective review of 150 pediatric(More)
INTRODUCTION Thyroid cancer incidence in Korea is the highest in the world and has recently increased steeply. However, factors contributing to this sudden increase have not been fully elucidated, and few studies have explored the postoperative prognosis. The Thyroid Cancer Longitudinal Study (T-CALOS) was initiated with three aims: (1) to identify factors(More)
Methods We evaluated 153 patients (28males) diagnosed younger than 20 years old, managed during 1980 through 2013 (median 7.0 years of duration). Good or poor outcome (persistence or recurrence) was analyzed in 126 patients followed for at least 12 months. Predictors for recurrence were analyzed among 108 pediatric PTC patients. Adult PTC patients (n =(More)
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