Hooman Mosannen Mozaffari

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PURPOSE Developmental pathways such as Wnt and Notch are involved in different cellular functions from the cell cycle regulation to self-renewal. Therefore, aberrations in these pathways may cause tumorigenesis. Msi1 has a critical regulatory role for the Wnt and Notch pathways. In the present study, we have assessed the probable correlation between the(More)
INTRODUCTION Lead poisoning is a major public health risk which may involve major organs. Recently, there have been reports of opioid adulteration with lead in Iran. The following case report is the first of its kind in that intrahepatic cholestasis due to lead toxicity has been described. CASE PRESENTATION A 65-year-old man presented to the emergency(More)
Deregulation of developmental signaling pathways such as Wnt/b-catenin and NOTCH are commonly observed in different cancers. A normal wnt pathway is essential for development and tissue homeostasis to preserve a normal balance between the differentiation and proliferation. PYGO2 is the main transcription factor of wnt pathway, while Msi1 is one of the wnt(More)
1 Radiology Department, Mashhad branch, Islamic Azad University, Mashhad, Iran 2 Gasteroenterology and Hepatology Department, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran 3 Gastroenterology and Hepatology Research Center, Mashhad University of Medical Sciences, Mashhad, Iran 4 Surgical Oncology Research Center, Mashhad(More)
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