Hongzhang Yin

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This paper proposes a coevolutionary optimization algorithm called DCOA. DCOA mainly focuses on how to adjust sub-population size self-adaptively so as to improve the optimizing performance. To achieve this, a strategy is introduced which consists of three rules: internal competition, external competition and spontaneous growth rules. These rules can(More)
Enterovirus 71 (EV71) is a common pathogen for hand, foot, and mouth disease (HFMD), which has significant morbidity and mortality, and for which children aged 6-59 months age are at highest risk. Due to lack of effective treatment options, control of EV71 epidemics has mainly focused on development of EV71 vaccines. Clinical trials have been completed on 3(More)
The immunological assays for detection of antibodies against SARS-CoV were developed in-house and some of them are available commercially. However, the antigens used in these assays differed. In order to validate the reliability of these assays, the standard panel should be established. In this study, we have expressed and purified severe acute respiratory(More)
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