Hongyu Jia

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BACKGROUND Influenza A(H7N9) viruses isolated from humans show features suggesting partial adaptation to mammals. To provide insights into the pathogenesis of H7N9 virus infection, we compared risk factors, clinical presentation, and progression of patients hospitalized with H7N9, H5N1, and 2009 pandemic H1N1 (pH1N1) virus infections. METHODS We compared(More)
BACKGROUND There is limited data on the clinical outcome of patients with pandemic H1N1 (pH1N1) pneumonia who received oseltamivir treatment, especially when the treatment was administered more than 48 hours after symptom onset. METHODS During the pandemic in 2009, a cohort of pH1N1 influenza pneumonia was built in China, and their clinical information(More)
Severe acute exacerbation in patients with chronic hepatitis B is a unique clinical presentation that results in high mortality. To compare the efficacy of 4 weeks of entecavir or lamivudine therapy in patients with severe acute exacerbation caused by chronic hepatitis B, 65 patients were retrospectively analyzed. The groups received 0.5 mg entecavir (group(More)
Tuberculosis (TB) remains a major public health concern worldwide. Previous studies have demonstrated that IL-17 plays an important role in initial immune response and is involved in both immune-mediated protection and pathology following infection with Mycobacterium tuberculosis (MTB). However, the alterations and regulation of plasma IL-17 level during TB(More)
The aim of the present study was to investigate the inhibitory effect of specific mimic peptides targeting duck hepatitis B virus polymerase (DHBVP) on duck hepatitis B virus (DHBV) replication in primary duck hepatocytes. Phage display technology (PDT) was used to screen for mimic peptides specifically targeting DHBVP and the associated coding sequences(More)
A novel classification algorithm based on rough sets and relevance vector machine classifier is proposed in this paper. Relevance vector machine is a novel support vector machine with Bayesian framewor.As redundant features can affect the classification performance of relevance vector machine, rough sets can simplify the redundant features which can improve(More)
A rabbit model of traumatic optic nerve injury, established by occlusion of the optic nerve using a vascular clamp, was used to investigate the effects of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor antagonist GYKI 52466 on apoptosis of retinal ganglion cells following nerve injury. Hematoxylin-eosin staining and a terminal(More)
The strain energy absorption of shape memory alloy (SMA) bars and beams under tension and bending loading was studied. A theoretical model is presented that can give quantitative relations between the martensite fraction, the applied load, and the strain energy absorbed in the shape memory alloy (SMA). It was found analytically that the super-elastic SMA(More)
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