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A genome-scale genetic interaction map was constructed by examining 5.4 million gene-gene pairs for synthetic genetic interactions, generating quantitative genetic interaction profiles for approximately 75% of all genes in the budding yeast, Saccharomyces cerevisiae. A network based on genetic interaction profiles reveals a functional map of the cell in(More)
A genetic interaction network containing approximately 1000 genes and approximately 4000 interactions was mapped by crossing mutations in 132 different query genes into a set of approximately 4700 viable gene yeast deletion mutants and scoring the double mutant progeny for fitness defects. Network connectivity was predictive of function because interactions(More)
Dempster-Shafer evidence theory (DSET) is a popular paradigm for dealing with uncertainty and imprecision. Its corresponding evidential reasoning framework is theoretically attractive. However, there are outstanding issues that hinder its use in real-life applications. Two prominent issues in this regard are 1) the issue of basic probability assignments(More)
ETHNOPHARMACOLOGICAL RELEVANCE Saposhnikovia divaricata (SD), called "Fangfeng" in China, is commonly used in clinical compound prescription for treatment of rheumatoid arthritis (RA), but its actions on RA have not been clarified. The present study aims to determine the anti-inflammatory activity of SD chromone extract (SCE), the major bioactive component(More)
www.MaterialsViews.com C O M Graphene-On-Silicon Schottky Junction Solar Cells M U N I By Xinming Li , Hongwei Zhu , * Kunlin Wang , * Anyuan Cao , Jinquan Wei , Chunyan Li , Yi Jia , Zhen Li , Xiao Li , and Dehai Wu C A IO N Graphene, a single atomic layer of carbon hexagons, has stimulated a lot of research interest owing to its unique structure and(More)
We generated a global genetic interaction network for Saccharomyces cerevisiae, constructing more than 23 million double mutants, identifying about 550,000 negative and about 350,000 positive genetic interactions. This comprehensive network maps genetic interactions for essential gene pairs, highlighting essential genes as densely connected hubs. Genetic(More)
This paper extends a conventional discounting scheme commonly used with the Dempster-Shafer evidential reasoning to deal with conflict. The extended discounting scheme is able to augment, discount, and oppose existing evidence structures when discounting factors take values in different ranges. To show its effectiveness, the scheme is employed for detecting(More)
OBJECTIVE To assess the effect of volume-targeted ventilation (VTV) compared with pressure-limited ventilation (PLV) in preterm infants. METHOD We searched the Cochrane Library (Issue 3, 2013), PubMed (1966 to 5 March 2013), China National Knowledge Infrastructure (CNKI) and periodical databases (1979 to 5 March 2013). We selected randomised controlled(More)