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Intrusion detection is a surveillance problem of practical import that is well suited to wireless sensor networks. In this paper, we study the application of sensor networks to the intrusion detection problem and the related problems of classifying and tracking targets. Our approach is based on a dense, distributed, wireless network of multi-modal(More)
We address the challenges of bursty convergecast in multi-hop wireless sensor networks, where a large burst of packets from different locations needs to be transported reliably and in real-time to a base station. Via experiments on a 49 MICA2 mote sensor network using a realistic traffic trace, we determine the primary issues in bursty convergecast, and(More)
Project ExScal (for extreme scale) fielded a 1000+ node wireless sensor network and a 200+ node peer-to-peer ad hoc network of 802.11 devices in a 13km by 300m remote area in Florida, USA during December 2004. In comparison with previous deployments, the ExScal application is relatively complex and its networks are the largest ones of either type fielded to(More)
We present Sprinkler, a reliable data dissemination service for wireless embedded devices which are constrained in energy, processing speed, and memory. Sprinkler embeds a virtual grid over the network whereby it can locally compute a connected dominating set of the devices to avoid redundant transmissions ,and a transmission schedule to avoid collisions.(More)
Prostate cancer (PrCa) is the most frequently diagnosed cancer in males in developed countries. To identify common PrCa susceptibility alleles, we previously conducted a genome-wide association study in which 541,129 SNPs were genotyped in 1,854 PrCa cases with clinically detected disease and in 1,894 controls. We have now extended the study to evaluate(More)
Noninvasive systemic gene delivery to the central nervous system (CNS) has largely been impeded by the blood-brain barrier (BBB). Recent studies documented widespread CNS gene transfer after intravascular delivery of recombinant adeno-associated virus 9 (rAAV9). To investigate alternative and possibly more potent rAAV vectors for systemic gene delivery(More)
The <i>Kansei</i> testbed at The Ohio State University is designed to facilitate research on networked sensing applications at scale. <i>Kansei</i> embodies a unique combination of characteristics as a result of its design focus on sensing and scaling: (i) Heterogeneous hardware infrastructure with dedicated node resources for local computation, storage,(More)
MicroRNA-155 (miR-155) is overexpressed in many human cancers; however, the mechanisms by which miR-155 functions as a putative oncomiR are largely unknown. Here, we report that the tumor suppressor gene suppressor of cytokine signaling 1 (socs1) is an evolutionarily conserved target of miR-155 in breast cancer cells. We found that mir-155 expression is(More)
BACKGROUND The association between hepatitis B virus (HBV) mutations and hepatocarcinogenesis remains controversial because of conflicting data in the literature. We conducted a meta-analysis of case-control and cohort studies to examine HBV PreS, enhancer II (EnhII), basal core promoter (BCP), and precore mutations in relation to the risk of hepatocellular(More)
OBJECTIVE Little is known about clinical features associated with the risk of recurrence in patients with bipolar disorder receiving treatment according to contemporary practice guidelines. The authors looked for the features associated with risk of recurrence. METHOD The authors examined prospective data from a cohort of patients with bipolar disorder(More)