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Novel molecular markers for cancer progression are valuable for the diagnosis and evaluation of treatment efficacies of the diseases. Expression of inosine 5'-monophosphate dehydrogenase type II (IMPDH2), a rate-limiting enzyme in the de novo guanine nucleotide biosynthesis, is up-regulated in various neoplasms, including prostate cancer and patient serum.(More)
Smartphone fever along with roaring mobile traffic pose great challenges for cellular networks to provide seamless wireless access to end users. Operators and vendors realize that new techniques are required to improve spectrum efficiency to meet the ever increasing user demand. In this article, we exploit the great opportunities provided by cognitive radio(More)
The existing learning theories and learning technology systems are faced with quite many problems in meeting educational challenges of the knowledge age. Based on the vast study of the learning models and technology systems, we put forward a theoretical framework of synergistic learning and develop a set of tools, such as synergistic building technology(More)
The p53 tumor suppressor functions as a transcription factor and plays a pivotal role in regulation of cellular response to DNA damage by activating various genes including those involved in cell cycle arrest. p53 stability is essential for its function during stress response; however, the molecular mechanism for DNA damage-induced stabilization of p53 is(More)
The effects of surgically implanted dummy ultrasonic transmitters on growth, survival and transmitter retention of bighead carp Hypophthalmichthys nobilis were investigated from October to November 2010. Before the surgery, 162 bighead carps were divided into three groups: 1) control group: handling but no tagging; 2) sham group: surgical procedure without(More)
The gradual emerging of resistance to imatinib urgently calls for the development of new therapy for chronic myeloid leukemia (CML). The fusion protein Bcr-Abl, which promotes the malignant transformation of CML cells, is mainly located in the cytoplasm, while the c-Abl protein which is expressed in the nucleus can induce apoptosis. Based on the(More)
The irradiation response of a DC-DC power converter was studied. During the test, the characteristic parameter of DC-DC power converter such as input current and output voltage increased slowly with empty load, and DC-DC power converter was unsteady and the characteristic parameter was strongly influenced by the total-dose when fully loaded. It was(More)