Hongwei Duan

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Mitochondrial-dependent apoptosis plays an important role in the degeneration of dopaminergic neurons in Parkinson’s disease (PD). Methyl-4-phenyl-1,2,3,6-tetra- hydropyridine (MPTP), the most widely used neurotoxin to simulate PD, is converted to 1-methyl-4-phenylpyridinium (MPP+) in vivo. MPP+ induces excessive intracellular reactive oxygen species (ROS),(More)
Parkinson's disease (PD) is the second most common neurodegenerative disease. Although the etiology of PD is not completely understood, it is well-documented that oxidative stress and Ca(2+)-mediated cellular damage play important roles in the progression of PD. 2-[[(1,1-Dimethylethyl)oxidoimino]-methyl]-3,5,6-trimethylpyrazine (TBN), a novel nitrone(More)
This article highlights our recent achievement on directing nanoparticles to self-assemble at the water/oil interface. We demonstrate that the contact angle of 90u is prerequisite for nanoparticles to localize at the interface, which is determined by the terminal groups of the capping ligands. With this peculiar surface wettability, nanoparticles of(More)
To circumvent the bottlenecks of non-flexibility, low sensitivity, and narrow workable detection range of conventional biosensors for biological molecule detection (e.g., dopamine (DA) secreted by living cells), a new hybrid flexible electrochemical biosensor has been created by decorating closely packed dendritic Pt nanoparticles (NPs) on freestanding(More)
  • Lingkui Meng, Jiyuan Li, Zidan Chen, Wenjun Xi E A, Deqing Chen, Hongwei Duan
  • 2011
Temperature-Vegetation Dryness Index (TVDI) is one of the agriculture drought indexes. This paper presents a data composite method which improves the calculation of TVDI through taking the time of pixel into consideration, and the adaptability of TVDI in drought assessment has also enhanced significantly. First, the Normalized Difference Vegetation Index(More)
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