Hongmei Jian

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Thermal motions in supercoiled DNA are studied by Brownian dynamics (BD) simulations with a focus on the site juxtaposition process. It had been shown in the last decade that the BD approach is capable of describing actual times of large-scale DNA motion. The bead model of DNA used here accounts for bending and torsional elasticity as well as the(More)
base pairs) shows excellent agreement as well. This lends confidence to the A carefully parameterized and tested simulation procedure for predictive ability of our model and sets the groundwork for further studying the dynamic properties of long linear DNA, based on a work on circular DNA. We conclude with results of such a predictive representation that(More)
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