Hongling Fan

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Minocylcine, a tetracycline derivate, has been shown to cross the blood-brain barrier and enter the central nervous system. In this study, cerebral ischemia-reperfusion injury models were established using the suture method, and minocycline was immediately injected intraperitoneally after cerebral ischemia-reperfusion (22.5 mg/kg, initially 45 mg/kg) at a(More)
Over-production of nitric oxide is pathogenic for neuronal apoptosis around the ischemic area fol-lowing ischemic brain injury. In this study, an apoptotic model in rat hippocampal neurons was tablished by 0.5 mmol/L 3-morpholinosyndnomine (SIN-1), a nitric oxide donor. The models were then cultured with 0.1 mmol/L of(More)
Abstract: In this paper, motivated by the research on qualitative properties of solutions for fractional differential-integro equations, some new Gronwall-Bellman type inequalities in two independent variables are established. Based on these inequalities, explicit bounds for unknown functions concerned are derived. As for applications, we apply the(More)
  • Hongling Fan
  • 2010 2nd International Conference on Computer…
  • 2010
Let T be a time scale. In this paper, we study the existence of positive solutions for the following nonlinear second-order m-point boundary value problem with sign changing coefficient on time scales {u<sup>&#x0394;&#x2207;</sup>(t)+f(t,u(t))=0, 0&lt;;t&lt;;T, u<sup>&#x0394;</sup>(0) = &#x03A3;<sub>i=1</sub><sup>m-2</sup>(More)
Apoptosis in cultured rat hippocampal neurons was induced using the nitric oxide donor 3-morpholinosydnonimine, and cells were treated with the chloride channel blocker, 4,4-diisothiocyanatostilbene-2,2'-disulfonic acid. Results showed that the survival rate of neurons was significantly increased after treatment with(More)
In this paper, we consider three-point boundary value problem (&#x03C6;<sub>p</sub>(u'))' + a(t)f(u) = 0, 0 &lt;; t &lt;; 1 where &#x03C6;<sub>p</sub>(u) = |u|<sup>p-2</sup>u, p &gt; 1, subject to nonlinear boundary conditions. We show that there exist positive solution and countably many positive solutions by fixed point theorems in a cone.
An ischemic-hypoxic animal model was established using right common carotid artery occlusions and inhalation of low concentrations of oxygen in mice. At 10 days after the ischemic-hypoxic injuries, saline-treated mice exhibited significantly prolonged escape latencies in water-maze tests and significantly shorter memory latencies and more mistakes in(More)
Inhomogeneity exists extensively in many real excitable media. In this paper, we divide the whole space into two parts by a straight line and investigate the effect of two-part inhomogeneity on dynamics of spiral wave by their tip motions. In the test simulation, let the excitable parameters of the two division spaces take different values. Numerical(More)
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